Results 41 to 50 of about 25,953 (267)
Advanced Science, EarlyView.A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang +7 more
wiley +1 more source
Effect of Iron Chelators on Methemoglobin and Thrombin Preconditioning. [PDF]
, 2012 Cell loss immediately adjacent to an intracerebral hemorrhage may be mediated in part by the toxicities of extracellular hemoglobin (Hb) and thrombin.
Chen-Roetling, Jing +2 more
core +2 more sources
BZW1 Drives Immune Evasion in Lung Adenocarcinoma via Ferroptosis Suppression
Advanced Science, EarlyView.BZW1 attenuates ferroptosis by competitively binding NCOA4 and suppress ferrtinophagy‐mediated iron release. The depletion of BZW1 triggers lipid peroxidation through iron homeostasis. Extracellularly, BZW1 attenuates immunogenic cell death and reinvigorates cytotoxic T‐cell responses.
Linyao Zhao +9 more
wiley +1 more source
Trypanotoxic activity of thiosemicarbazone iron chelators. [PDF]
, 2015 Only a few drugs are available for treating sleeping sickness and nagana disease; parasitic infections caused by protozoans of the genus Trypanosoma in sub-Saharan Africa.
Ellis, S, Sexton, DW, Steverding, D
core +1 more source
Advanced Science, EarlyView.The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng +10 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen +10 more
wiley +1 more source
Investigating subsumption in DL-based terminologies: A case study in SNOMED CT [PDF]
, 2004 Formalisms such as description logics (DL) are sometimes expected to help terminologies ensure compliance with sound ontological principles. The objective of this paper is to study the degree to which one DL-based biomedical terminology (SNOMED
Bodenreider, Olivier +3 more
core +1 more source
The Availability of Iron Is Involved in the Murine Experimental Toxoplasma gondii Infection Outcome
Microorganisms, 2020 Iron is an important constituent of our environment, being necessary for both mammalian and pathogenic protozoa survival. Iron-containing proteins exert a wide range of biological processes such as biodegradation and biosynthesis, as well as immune ...
Mário Cézar Oliveira +5 more
doaj +1 more source
Influence of iron- and zinc-chelating agents on neutrophil extracellular trap formation
Central European Journal of Immunology, 2021 Release of neutrophil extracellular traps (NETs) is one of the neutrophils’ mechanisms involved in the response to infection. NETs are released from the cell in response to a biological or synthetic stimulus to entrap, immobilize and kill pathogens ...
Weronika Kuźmicka +5 more
doaj +1 more source
In-vitro Apoptotic Effects of Deferoxamine on the Glioblastoma Cell Line
Iranian South Medical Journal, 2019 Background: Research suggests the inhibitory effects of deferoxamine as an iron chelator on erythroleukemia cells. The present study was conducted to investigate the effects of deferoxamine on B92 cells as a model of glial cells carcinoma.
Mahtab Pourkamalzadeh +1 more
doaj