Results 41 to 50 of about 18,326 (214)

The regulatory mechanism of deferoxamine spray in promoting the healing of chronic wounds in third-degree burns

Yixue xinzhi zazhi
Objective To explore the effects and its mechanism of deferoxamine spray on the healing process of chronic wounds from third-degree burns. Methods Screening the concentration of deferoxamine spray suitable for subsequent experiments through ...
CHAI Langjie, LI Qin, GUO Liang, HUANG Jianglong   +3 more
doaj   +1 more source

Gestational Changes in Placental Iron Homeostasis are Associated With Ferroptosis-Associated Redox Signaling and Trophoblast Behavior. [PDF]

FASEB J
This graphical abstract summarizes gestational changes in placental iron homeostasis and their relationship to ferroptosis‐associated molecular features. In trophoblast cells, experimentally induced sublethal iron‐dependent redox perturbation modulates migration and invasion without causing overt ferroptotic cell death, whereas iron chelation or ...
Jiang W, Yang Y, Yuan X, Deng W, Kilby MD, Baker PN, Tong C, Yang Y.   +7 more
europepmc   +2 more sources

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Deferoxamine Preconditioning of Irradiated Tissue Improves Perfusion and Fat Graft Retention [PDF]

, 2018
BACKGROUND: Radiation therapy is a mainstay in the treatment of many malignancies, but collateral damage to surrounding tissue, with resultant hypovascularity, fibrosis, and atrophy, can be difficult to reconstruct. Fat grafting has been shown to improve
Dre Irizarry, Chung, Natalie, Irizarry, Dre, Dung Nguyen, Longaker, Michael T, Derrick C. Wan, Arash Momeni, Lee, Gordon K, Natalie Chung, Geoffrey C. Gurtner, Michael T. Longaker, Charles P. Blackshear, Nguyen, Dung, Flacco, John, John Flacco, Gordon K. Lee, Wan, Derrick C, Gurtner, Geoffrey C, Blackshear, Charles P, Momeni, Arash   +19 more
core   +1 more source

Abrupt increased serum creatinine in a hyperferritinemia patient treated with deferoxamine after cord blood transplantation: a case report with literature review

Journal of Pharmaceutical Health Care and Sciences, 2023
Background Erythrocyte transfusion is an indispensable component of supportive care after hematopoietic stem cell transplantation (HSCT). However, HSCT recipients are susceptible to the development of acute kidney injury (AKI) with multifactorial causes.
Hirokazu Nakayama, Yoshimasa Kamoda, Michiya Tanuma, Toshiaki Kato, Kensuke Usuki   +4 more
doaj   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Intraperitoneal deferoxamine therapy for iron overload in children undergoing CAPD [PDF]

, 1989
Intraperitoneal deferoxamine therapy for iron overload in children undergoing CAPD. We treated three children with renal failure and chronic iron overload with intraperitoneal deferoxamine therapy. Each child had an elevated serum ferritin level, a dense
Andreoli, Sharon P., Cohen, Mervyn
core   +1 more source

Iron Neurotoxicity and Protection by Deferoxamine in Intracerebral Hemorrhage

Frontiers in Molecular Neuroscience, 2022
Intracerebral hemorrhage (ICH) is a subtype of stroke that is characterized by high morbidity and mortality, for which clinical outcome remains poor. An extensive literature indicates that the release of ferrous iron from ruptured erythrocytes in the ...
Zhe Li, Zhe Li, Zhe Li, Yang Liu, Yang Liu, Yang Liu, Ruixue Wei, Ruixue Wei, Ruixue Wei, Suliman Khan, Suliman Khan, Suliman Khan, Ruiyi Zhang, Ruiyi Zhang, Ruiyi Zhang, Yan Zhang, Yan Zhang, Yan Zhang, Voon Wee Yong, Mengzhou Xue, Mengzhou Xue, Mengzhou Xue   +21 more
doaj   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Deferoxamine effect on the delay phenomenon

, 2021
Tıpta UzmanlıkRekonstrüksiyon başarısını ve flep yaşayabilirliğini arttırmak amacıyla bir çok cerrahi teknik ve ilaç denenmiştir. Deferoksaminin yeni damar oluşumunu arttırdığı ve yara iyileşmesine olumlu katkısının olduğu bilinmekle beraber cerrahi ...
Erdem, Ufuk
core   +1 more source