Results 51 to 60 of about 16,985 (220)
Bone histologic response to deferoxamine in aluminum–related bone disease [PDF]
Bone histologic response to deferoxamine in aluminum–related bone disease. We have examined the changes in bone histology in 28 uremic patients after long–term treatment with the aluminum chelator, deferoxamine.
Endres, David B. +7 more
core +1 more source
In-vitro Apoptotic Effects of Deferoxamine on the Glioblastoma Cell Line
Background: Research suggests the inhibitory effects of deferoxamine as an iron chelator on erythroleukemia cells. The present study was conducted to investigate the effects of deferoxamine on B92 cells as a model of glial cells carcinoma.
Mahtab Pourkamalzadeh +1 more
doaj
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
Deferoxamine Reduces Early Metabolic Failure Associated With Severe Cerebral Ischemic Acidosis in Dogs [PDF]
Background and Purpose Postischemic metabolic injury may be mediated by acidosis and tissue bicarbonate depletion, with consequent iron mobilization and oxygen radical formation during reperfusion.
Kathleen K. Blizzard +3 more
core +1 more source
The Availability of Iron Is Involved in the Murine Experimental Toxoplasma gondii Infection Outcome
Iron is an important constituent of our environment, being necessary for both mammalian and pathogenic protozoa survival. Iron-containing proteins exert a wide range of biological processes such as biodegradation and biosynthesis, as well as immune ...
Mário Cézar Oliveira +5 more
doaj +1 more source
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner +10 more
wiley +1 more source
Induction of embryonal carcinoma cell differentiation by deferoxamine, a potent therapeutic iron chelator [PDF]
We investigated the effects of deferoxamine on the differentiation of embryonal carcinoma F9 cells. Deferoxamine, a widely used therapeutic agent for thalassemia and iron overload, was found to induce F9 cell differentiation and to have some unique ...
Yuko Ido +9 more
core +1 more source
A Novel Star Like Eight-Arm Polyethylene Glycol-Deferoxamine Conjugate for Iron Overload Therapy
The traditional iron chelator deferoxamine (DFO) has been widely used in the treatment of iron overload disease. However, DFO has congenital disadvantages, including a very short circular time and non-negligible toxicity.
Bohong Yu +5 more
doaj +1 more source
The amphiphilic copolymer incorporating a hydrophobic chain conjugated with artesunate into a biocompatible sulfobetaine polymer is synthesized by solid‐state copolymerization of sulfobetaine methacrylate and methacrylamide derivative conjugating artesunate.
Naoki Doi +9 more
wiley +1 more source
Effect of intravenous Deferoxamine concomitant use with blood transfusion on serum ferritin in thalassemia major patients [PDF]
Background: Subcutaneous Deferoxamineis often not tolerated by patients and its rejection leads to iron overload with its complications. So, other methods with better toleration and reduction of Deferoxamine consumption are necessary.
Amani, Firouz +3 more
core +2 more sources

