Results 51 to 60 of about 16,985 (220)

Bone histologic response to deferoxamine in aluminum–related bone disease [PDF]

open access: yes, 1987
Bone histologic response to deferoxamine in aluminum–related bone disease. We have examined the changes in bone histology in 28 uremic patients after long–term treatment with the aluminum chelator, deferoxamine.
Endres, David B.   +7 more
core   +1 more source

In-vitro Apoptotic Effects of Deferoxamine on the Glioblastoma Cell Line

open access: yesIranian South Medical Journal, 2019
Background: Research suggests the inhibitory effects of deferoxamine as an iron chelator on erythroleukemia cells. The present study was conducted to investigate the effects of deferoxamine on B92 cells as a model of glial cells carcinoma.
Mahtab Pourkamalzadeh   +1 more
doaj  

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Deferoxamine Reduces Early Metabolic Failure Associated With Severe Cerebral Ischemic Acidosis in Dogs [PDF]

open access: yes, 1995
Background and Purpose Postischemic metabolic injury may be mediated by acidosis and tissue bicarbonate depletion, with consequent iron mobilization and oxygen radical formation during reperfusion.
Kathleen K. Blizzard   +3 more
core   +1 more source

The Availability of Iron Is Involved in the Murine Experimental Toxoplasma gondii Infection Outcome

open access: yesMicroorganisms, 2020
Iron is an important constituent of our environment, being necessary for both mammalian and pathogenic protozoa survival. Iron-containing proteins exert a wide range of biological processes such as biodegradation and biosynthesis, as well as immune ...
Mário Cézar Oliveira   +5 more
doaj   +1 more source

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner   +10 more
wiley   +1 more source

Induction of embryonal carcinoma cell differentiation by deferoxamine, a potent therapeutic iron chelator [PDF]

open access: yes, 1997
We investigated the effects of deferoxamine on the differentiation of embryonal carcinoma F9 cells. Deferoxamine, a widely used therapeutic agent for thalassemia and iron overload, was found to induce F9 cell differentiation and to have some unique ...
Yuko Ido   +9 more
core   +1 more source

A Novel Star Like Eight-Arm Polyethylene Glycol-Deferoxamine Conjugate for Iron Overload Therapy

open access: yesPharmaceutics, 2020
The traditional iron chelator deferoxamine (DFO) has been widely used in the treatment of iron overload disease. However, DFO has congenital disadvantages, including a very short circular time and non-negligible toxicity.
Bohong Yu   +5 more
doaj   +1 more source

Biocompatible Sulfobetaine Polymer‐Artemisinin Conjugates Inducing Ferroptosis in Cancer Cells: Synthesis by Mechanochemical Solid‐State Polymerization and Characterization

open access: yesMacromolecular Rapid Communications, EarlyView.
The amphiphilic copolymer incorporating a hydrophobic chain conjugated with artesunate into a biocompatible sulfobetaine polymer is synthesized by solid‐state copolymerization of sulfobetaine methacrylate and methacrylamide derivative conjugating artesunate.
Naoki Doi   +9 more
wiley   +1 more source

Effect of intravenous Deferoxamine concomitant use with blood transfusion on serum ferritin in thalassemia major patients [PDF]

open access: yes, 2017
Background: Subcutaneous Deferoxamineis often not tolerated by patients and its rejection leads to iron overload with its complications. So, other methods with better toleration and reduction of Deferoxamine consumption are necessary.
Amani, Firouz   +3 more
core   +2 more sources

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