Results 71 to 80 of about 18,326 (214)

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Predicting Mesoscopic Larmor Frequency Shifts in Ex Vivo Porcine Optic Nerve

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Larmor frequency shifts in white matter (WM) vary with fiber orientation due to anisotropic microstructure. Since clinical voxels are significantly larger than these microscopic frequency variations, the measured signal represents a bulk average of local shifts.
Anders Dyhr Sandgaard, André Pampel, Roland Müller, Niklas Wallstein, Toralf Mildner, Carsten Jäger, Markus Morawski, Aage Kristian Olsen Alstrup, Harald E. Möller, Sune Nørhøj Jespersen   +9 more
wiley   +1 more source

Induction of embryonal carcinoma cell differentiation by deferoxamine, a potent therapeutic iron chelator [PDF]

, 1997
We investigated the effects of deferoxamine on the differentiation of embryonal carcinoma F9 cells. Deferoxamine, a widely used therapeutic agent for thalassemia and iron overload, was found to induce F9 cell differentiation and to have some unique ...
Yuko Ido, Keiichi Tanaka, Tanaka, Tetsuya, Ido, Yuko, Muto, Norio, Tanaka, Keiichi, Norio Itoh, Itoh, Norio, Norio Muto, Tetsuya Tanaka   +9 more
core   +1 more source

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy, Yoon Ho Lee, Ali Salehi Farid, Heydar Moravej, Sina Djafari Rouhani, Jennifer E. Rowley, Mohammad Rashidian, Mark D. Distefano   +7 more
wiley   +2 more sources

Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: To report cases of use of chelation therapy during pregnancy which resulted in favorable outcomes for the babies. Materials and methods: In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian ...
Maria Grazia Piccioni, Carmela Capone, Flaminia Vena, Valentina Del Negro, Michele Carlo Schiavi, Valentina D'Ambrosio, Antonella Giancotti, Maria Paola Smacchia, Roberto Brunelli   +8 more
doaj   +1 more source

Sulfasalazine Enhances Copper Toxicity in Danio rerio Larvae: Divergent Protective Roles of Deferoxamine and Ferrostatin‐1

Environmental Toxicology, EarlyView.
ABSTRACT Copper is an environmental contaminant capable of disrupting redox homeostasis and impairing antioxidant defenses in aquatic organisms, thereby increasing susceptibility to oxidative stress. The cystine/glutamate antiporter (system xc−) plays a central role in maintaining intracellular glutathione (GSH) levels, a major antioxidant defense ...
Maria Vitória Takemura Mariano, Pedro Henrique Vicenzi, Vitor Oliveira de Rosso, Mauro Eugênio Medina Nunes, Layla da Silva Braga, Analía Del Valle Garnero, Ricardo José Gunski, Marcelo Farina, Thaís Posser, Jeferson Luis Franco   +9 more
wiley   +1 more source

m6A‐Related Regulation of Ferroptosis Contributes to Nasal Epithelial Barrier Dysfunction in Allergic Rhinitis

Allergy, EarlyView.
This study uses human nasal epithelial cells and BALB/c mice to evaluate the role and molecular mechanism of ferroptosis in HDM‐induced AR, focusing on ferroptosis‐related responses and nasal epithelial barrier disruption. HDM exposure induces lipid peroxidation‐driven ferroptosis and epithelial barrier disruption.
Zehua Lin, Baoai Han, Qiang Xie, Aikebaier Tuohuti, Weisong Cai, Peng Zhou, Jiahao Meng, Qiuyang Fu, Zuhong He, Xiong Chen   +9 more
wiley   +1 more source

Effect of intravenous Deferoxamine concomitant use with blood transfusion on serum ferritin in thalassemia major patients [PDF]

, 2017
Background: Subcutaneous Deferoxamineis often not tolerated by patients and its rejection leads to iron overload with its complications. So, other methods with better toleration and reduction of Deferoxamine consumption are necessary.
Amani, Firouz, Araghchin, Samira, Farzaneh, Esmaeil, Fathi, Afshin   +3 more
core   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Deferoxamine Inhibits Canine Parvovirus by Suppressing Ferroptosis and Viral Replication

Veterinary Sciences
CPV is a highly pathogenic virus that enters host cells via the TFR, but its pathogenic mechanisms are not fully understood. In this study, we demonstrated that CPV infection induces ferroptosis in CRFK cells, characterized by elevated lipid peroxidation,
Kai Yu, Haoyuan Ma, Siqi Zhang, Jiawei Zhao, Jingrui Hao, Jialiang Xie, Hao Yu, Jianyou Jin, Xinpeng Ji, Shuoning Cao, Zheng Sun, Shujiang Xue, Shengwei Ji, Zhiqiang Xu, Chenghui Li, Rui Du, Xu Gao   +16 more
doaj   +1 more source