Results 91 to 100 of about 16,909 (214)
Dijiong Wu,1 Xiaowen Wen,2 Wenbin Liu,1 Huijin Hu,1 Baodong Ye,1 Yuhong Zhou1 1Department of Hematology, First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Internal ...
Wen X, Hu H, Ye B, Wu D, Zhou Y, Liu W
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Deferoxamine in thalassemia major.
Comment on: Survival in medically treated patients with homozygous beta-thalassemia. [N Engl J Med. 1994] Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major.
CAZZOLA, MARIO +2 more
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Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh +13 more
wiley +1 more source
Intra-ventricular delivery of the iron chelator deferoxamine provides protection in R6/2 HD mice.
Deferoxamine was delivered into the left ventricle of 6-week-old R6/2 HD mice at a dose-rate of 1-nmole / hour. Mice were analyzed daily before and after surgery for Rota-rod performance. A.
Linh Q. Lam (469736) +9 more
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Angiogenesis is vital for bone fracture healing and plays a significant role in the fate of orthopedic implants. The growth and maintenance of new blood vessels at the fracture site of patients is essential, which promotes the clinical outcome of plasma ...
Huan Liu +5 more
doaj +1 more source
Impaired Iron Metabolism in the Pathogenesis of Critical Conditions (an Experimental Study)
Objective: to study the pathogenetic value of iron metabolic disturbances in microcirculatory disorders and in the development of endotoxemia in the critical conditions caused by abdominal sepsis and bone injury.
Yu. P. Orlov +8 more
doaj +1 more source
PROTECTIVE EFFECT OF THE IRON CHELATOR DEFEROXAMINE ON CEREBRAL VASOSPASM
Experimental studies suggest the primary role of free radical products in the development of vasospasm. In the present study, the iron chelator deferoxamine was used at the time of subarachnoid hemorrhage to prevent chronic cerebral vasospasm.
KILINC, K +4 more
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Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
International audienceThe effect of amphoteric siderophore deferoxamine on the crystallization behavior of calcium carbonate was investigated under bioinspired conditions.
Pinna, N. +11 more
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