Results 81 to 90 of about 16,985 (220)
In vivo effects of curcumin and deferoxamine in experimental endometriosis [PDF]
, 2017 Background. Endometriosis is one of the most common chronic gynecological diseases. Objectives. The aim of the study was to examine the effects of curcumin and/or deferoxamine on cell proliferation in a rat model of endometriosis.
Uz, Yesim Hulya +6 more
core +1 more source
Hemodialysis International, EarlyView.ABSTRACT Background Iron overload in chronic kidney disease contributes to oxidative injury. The role of iron chelators, standard in transfusion‐related overload, remains unclear in chronic kidney disease. Aim To evaluate the efficacy and safety of iron chelators in adults with chronic kidney disease.
Humam Emad Rajha +6 more
wiley +1 more source
Coronary venous retroinfusion of deferoxamine reduces infarct size in pigs [PDF]
, 1991 The efficacy of coronary venous retroinfusion of the iron chelator deferoxamine was studied in 24 pentobarbital-anesthetized open chest pigs with a 60 min occlusion of the left anterior descending coronary artery followed by 3 h of reperfusion.
Nordlander, Rolf +6 more
core +1 more source
International Endodontic Journal, EarlyView.ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang +9 more
wiley +1 more source
Journal of Sleep Research, EarlyView.In 15 postoperative cardiac surgery patients, venous reactive oxygen species (ROS) measured by electron spin resonance (ESR) over 48 h showed no consistent circadian pattern. Higher ROS was associated with lower subjective sleep efficiency and more nocturnal awakenings, but not with other sleep measures.
K. Krawczyk +10 more
wiley +1 more source
Deferoxamine Inhibits Canine Parvovirus by Suppressing Ferroptosis and Viral Replication
Veterinary SciencesCPV is a highly pathogenic virus that enters host cells via the TFR, but its pathogenic mechanisms are not fully understood. In this study, we demonstrated that CPV infection induces ferroptosis in CRFK cells, characterized by elevated lipid peroxidation,
Kai Yu +16 more
doaj +1 more source
Toward optimizing the use of deferasirox: potential benefits of combined use with deferoxamine
Haematologica, 2013 Patients with β-thalassemia require iron chelation therapy to protect against progressive iron overload and non-transferrin-bound iron. Some patients fail to respond adequately to deferoxamine and deferasirox monotherapy while others have side effects ...
Robert W. Grady +5 more
doaj +1 more source
The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models
Photochemistry and Photobiology, EarlyView.This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva +5 more
wiley +1 more source
Indolent zygomycosis associated with deferoxamine chelation therapy [PDF]
, 1994 This paper describes a 71-year-old man with myelodysplasia who required multiple transfusions and subsequent deferoxamine chelation therapy and who then developed indolent cutaneous and probable pulmonary infection with Rhizopus species.
Bradley, Suzanne F. +5 more
core +1 more source
Sex and Gender Differences in Iron Chelation
BiomedicinesBackground/Objectives: In the absence of physiological mechanisms to excrete excessive iron, the administration of iron chelation therapy is necessary.
Sarah Allegra +3 more
doaj +1 more source