Results 1 to 10 of about 2,008 (113)

Osteoporosis in Thalassemia Major

Türk Osteoporoz Dergisi, 2012
Thalassemia Major is an inherited blood disorder which leads to ineffective erythropoiesis, bone marrow expansion, and skeletal deformity. In the last two decades the survival of the patients has improved considerably and osteoporosis has become a serious burden.
Pembe Hare Yiğitoğlu, Rengin Güzel
doaj   +3 more sources

Knowledge of Children and Adolescents with Beta Thalassemia Major about their Disease: An Assessment Study [PDF]

Egyptian Journal of Health Care, 2022
Background: Beta-thalassemia major is the most common hemoglobin disorder in the world. Assessing the knowledge of the children and adolescents regarding a beta- thalassemia major is important because helps to avoid complications.
Salma El Sayed Hassan, Randa M. Matter, Safy Salah Eldin AlRafay, Rahma Elsayed Abdel Aziz   +3 more
doaj   +1 more source

Major Thalassemia, Screening or Treatment: An Economic Evaluation Study in Iran [PDF]

International Journal of Health Policy and Management, 2022
BackgroundBeta-thalassemia minor and thalassemia major are an autosomal recessive disease with hypochromic, microcytic anemia, and morbidities, Today, therapeutic advances have significantly improved the life expectancy of thalassemia major patients, but
Firooz Esmaeilzadeh, Batoul Ahmadi, Sajad Vahedi, Saeed Barzegari, Abdolhalim Rajabi   +4 more
doaj   +1 more source

The Associations between HLA DQB1 different Alleles and β-thalassemia Major [PDF]

Minia Journal of Medical Research, 2020
Thalassemias are the commonest inherited hemoglobinopathies in the world. Approximately 68,000 children are born with various thalassemia syndromes each year. β-Thalassemia represents a major public health problem in Egypt. beta thalassemia. It is caused
Amel Kamal Eldin, ,Emad Abd El Naem, Mostafa Elsayed, Nada Zaki Mahmoud   +3 more
doaj   +1 more source

Changes in coagulation status in patients with β-thalassemia in Iraq: A case-control study

Medical Journal of Babylon, 2022
Background: The pathogenesis β-thalassemia is characterized by anemia resulting from reduced β-globin synthesis with low hemoglobin A (HbA) production and higher production of hemoglobin A2 (HbA2) and fetal hemoglobin (HbF).
Hussein Abdalzehra Wadaha, Hassan Dede Meshay, Mohammed Haseeb Khamees   +2 more
doaj   +1 more source

Evaluation of Factors influencing the birth of Thalassemia in Family Members with Thalassemia Major in Southeast Iran in 2021 [PDF]

Journal of Advanced Biomedical Sciences, 2023
Background & Objectives: Beta-thalassemia is one of the complex diseases that causes many social and economic problems for the patient and his family. This study aimed to investigate factors influencing the birth of thalassemia (intermedia or major) in ...
Majid Naderi, Sahar Najafi, Mohammad Hossein Ahmadi, Fariba Ramezani Siakhulak, Saeedeh Yaghoubi, Younes Sadeghi-Bojd   +5 more
doaj  

A Hematologic Disease in the Turkish Republic of Northern Cyprus: Thalassemia Major

Mediterranean Nursing and Midwifery, 2023
Thalassemia is an inherited hematologic disease in which the body makes an abnormal form of hemoglobin. Patients are diagnosed with thalassemia major due to severe anemia and clinical symptoms.
Hazel Şahin Tarım, Fatma Öz
doaj   +1 more source

Evaluation of the Association of Transferrin Receptor Type 2 Gene Mutation (Y250X) with Iron Overload in Major β-Thalassemia [PDF]

Archives of Razi Institute, 2021
Thalassemia is an inherited blood disorder in which the body produces defective hemoglobin. One of the important processes to reduce the complication of major β-thalassemia is blood transfusion that leads to elevated ferritin levels in the blood.
J Abdulmalek Jaafar, N. A. M Al-Rashedi
doaj   +1 more source

Determination of mutations in iron regulating genes of beta thalassemia major patients of Khyber Pakhtunkhwa, Pakistan

Molecular Genetics & Genomic Medicine, 2020
Background Hepcidin and hemochromatosis (HFE) are iron regulatory proteins that are encoded by HAMP and HFE genes. Mutation in either HAMP gene or HFE gene causes Hepcidin protein deficiency that can lead to iron overload in beta thalassemia patients ...
Maryam Shah, Lubna Danish, Najeeb U. Khan, Fakhar Zaman, Muhammad Ismail, Mehfooz Hussain, Ruqiya Pervaiz, Aqib Iqbal   +7 more
doaj   +1 more source

Psychopathology in thalassemia major

Pediatrics International, 2009
AbstractBackground:  Thalassemia major (TM) is a chronic disease with adverse emotional effects on both the child and the family. The aim of this study was to investigate the psychiatric state and behavioral problems of children with TM.Methods:  Twenty children diagnosed with TM and 34 healthy children were enrolled in this study carried out by the ...
Polat, A., Çakaloz, Burcu, Çakaloz, İnanç, İnan, Murat, Oguzhanoglu, N.K.   +4 more
openaire   +6 more sources