Results 21 to 30 of about 71,295 (266)

Overview of the current issues and advances in haemopoietic stem cell transplantation for β-thalassemia major

Thalassemia Reports, 2011
Bone marrow transplantation (BMT) is the only possible curative treatment for β-thalassemia major. The largest experience occurred in Pesaro, Italy, where the BMT was applied after a standard risk assessment.
S.S. Anak
doaj   +1 more source

Vacillating between distress and adaptation: a multi-perspective account of lived experiences of thalassemia major [PDF]

, 2011
Thalassemia major is a recessively inherited haematological disorder, which involves a complete lack or reduction of beta protein in the hemoglobin, causing life-threatening anemia.
Mufti, G.E.R.
core   +1 more source

Development of the Quality of Life Questionnaire (SF-36) for Patients with β-Thalassemia Major and β-Thalassemia Intermedia Based on Extended Rasch Analysis

, 2021
The quality of life (QoL) questionnaire (SF-36) contains 36 questions in eight subscales. It requires much time to fill in by the respondent. The objective of this study was to use Rasch models to develop a questionnaire that brings the desired outcome ...
Safizadeh, H, Sharifi, F, Bahrampour, A
core   +1 more source

How early can myocardial iron overload occur in Beta thalassemia major?

, 2014
BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
Gaohui Yang, Pan Hongfei, He, T, Lai, Y, Peng, P, Liu Rongrong, Long, X, Taigang He, Tan Shaohong, Liu, R, Hongfei Pan, Yang Weijia, Xingjiang Long, Rongrong Liu, Lai Yongrong, Yang Gaohui, He Taigang, Weijia Yang, Yang, G, Xinhua Zhang, Tan, S, Liling Long, Anderson Lisa, Lisa Anderson, Long Xingjiang, Yang, W, Zhang, X, Anderson, L, Peng Peng, Yongrong Lai, Zhang Xinhua, Long Liling, Pan, H, Shaohong Tan, Long, L   +34 more
core   +1 more source

The correlation between HLA class II and β-thalassemia major in Al-Karama teaching hospital

مجلة كلية الطب, 2016
Background: Thalassemia is a form of inherited autosomal recessive blood disorder characterized by abnormal formation of hemoglobin. Objective: Determine frequencies & association of HLA class II alleles (DRB1& DQB1) in Iraqi β-thalassemia major patients.
Sarmad M. Zeiny
doaj   +1 more source

Right ventricular volumes and function in thalassemia major patients in the absence of myocardial iron overload

, 2010
Aim: We aimed to define reference ranges for right ventricular (RV) volumes, ejection fraction (EF) in thalassemia major patients (TM) without myocardial iron overload.Methods and results: RV volumes, EF and mass were measured in 80 TM patients who had ...
Maciej Garbowski, He, TG, Maceira, A, Francisco Alpendurada, Banya Winston, He, T, Taigang He, Carpenter, JP, Smith, GC, Kirk, P, Shah, F, Maceira Alicia, Porter, JB, John B Porter, Banya, W, He Taigang, Walker, JM, Kirk Paul, Alicia Maceira, Alpendurada Francisco, Gillian C Smith, Porter John B, Smith Gillian C, Farrukh Shah, Pennell, DJ, Shah Farrukh, Pennell Dudley J, Deac Monica, Dudley J Pennell, Alpendurada, F, Paul Kirk, Winston Banya, Carpenter John-Paul, John-Paul Carpenter, Deac, M, J Malcolm Walker, Garbowski, M, Walker J Malcolm, Garbowski Maciej, Monica Deac   +39 more
core   +1 more source

β-thalassemia major evolution from β-thalassemia minor is associated with paternal uniparental isodisomy of chromosome 11p15

Haematologica, 2008
β-thalassemia major can be caused by homozygosity or compound heterozygosity for β-globin gene mutations (HBB gene). Most cases are inherited from parents who both have diseased alleles of the HBB gene.
Jan-Gowth Chang, Wen-Chan Tsai, Inn-Wen Chong, Chao-Sung Chang, Chyi-Chang Lin, Ta-Chih Liu   +5 more
doaj   +1 more source

Glycated Albumin as Marker for Early Hyperglycemia Detection in Adolescent with β Thalassemia Major

Indonesian Biomedical Journal, 2021
BACKGROUND: Hyperglycemia is one of the most common endocrine complications in children with β thalassemia major. Though the current diagnostic marker either requires fasting, has low reproducibility, or it is not an accurate for thalassemia patients ...
Dewinda Candrarukmi, Annang Giri Moelyo, Muhammad Riza   +2 more
doaj   +1 more source

Prevalence of orofacial changes in patients with β-thalassemia major in Karbala City, Iraq [PDF]

, 2014
Objectives: The aim of this study was to investigate findings of oral abnormalities or changes in these patients, and compare it to healthy control subjects.
Muhanned Salah Abulsattar, Ali Mihsen Al-Yassiri   +1 more
core   +2 more sources

Idiopathic Hypertriglyceridemia in Thalassemia Major: A Case Report [PDF]

National Journal of Laboratory Medicine, 2017
Thalassemia major is a severe hereditary haemolytic anaemia and is usually associated with normal serum lipid profile. But there are few reports in literature that hypertriglyceridemia can have an idiopathic association with β-thalassemia major.
Bhavya P Mohan, Prabhalekshmy KK, Letha V, Nisha TR   +3 more
doaj   +1 more source