Results 31 to 40 of about 71,330 (251)

Hypertriglyceridemia in a Baby with Thalassemia Major [PDF]

, 2020
Thalassemia is the most common inherited hemoglobin disorder around the world. It is usually associated with normal serum lipid profile. However, there are a few reports in literature that hypertriglyceridemia has an association with beta-thalassemia ...
Aditi Rawat, Poonam Agrawal, Saumya Pandey, Pratima Khare, Mrinal Gupta   +4 more
core   +1 more source

Prevalence of orofacial changes in patients with β-thalassemia major in Karbala City, Iraq [PDF]

, 2014
Objectives: The aim of this study was to investigate findings of oral abnormalities or changes in these patients, and compare it to healthy control subjects.
Muhanned Salah Abulsattar, Ali Mihsen Al-Yassiri   +1 more
core   +2 more sources

The correlation between HLA class II and β-thalassemia major in Al-Karama teaching hospital

مجلة كلية الطب, 2016
Background: Thalassemia is a form of inherited autosomal recessive blood disorder characterized by abnormal formation of hemoglobin. Objective: Determine frequencies & association of HLA class II alleles (DRB1& DQB1) in Iraqi β-thalassemia major patients.
Sarmad M. Zeiny
doaj   +1 more source

Evaluation of Bone Mineral Density in Children with Thalassemia Major [PDF]

, 2012
Aim: Fragile bones develop due to various factors in thalassemic patients. Even with optimum management, osteoporosis occurs, contributing to morbidity in majority of patients with thalassemia major (TM).
Abdullah Berk, Mesut Garipardıç, Özlem Gül Eser, Vedat Bakan, Fuat Özkan, Betül Bakan, Mehmet Alparslan Yılmaz   +6 more
core   +1 more source

Screening of Extended Family Members of Thalassemia Major Children as a Thalassemia Preventive Strategy [PDF]

, 2022
BACKGROUND: Thalassemia is considered as the most common single gene disorder worldwide. Preventive measures include identification of thalassemia carriers (traits) through screening, genetic counselling and prenatal diagnosis to reduce the incidence ...
Valvi, Chhaya T, Kamath, Pragathi A, Aarti Avinash Kinikar, Sonkawade, Naresh Dattatraya, Rahul M Dawre, Kulkarni, Rajesh K, Kinikar, Aarti Avinash, Pragathi A Kamath, Rajesh K Kulkarni, Chhaya T Valvi, Dawre, Rahul M, Naresh Dattatraya Sonkawade   +11 more
core   +2 more sources

Is There any Relationship Between the Repeated Complications of Sickle Cell Disease and the Potential Development of Acute Leukemia?

Oncology and Therapy
Sickle cell disease (SCD) is a severe monogenic hereditary hemoglobinopathy that is characterized by repeated clinical and biological manifestations able to generate stress erythopoiesis.
Giovanna Cannas, Mohamed Elhamri, Xavier Thomas   +2 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

β-thalassemia major evolution from β-thalassemia minor is associated with paternal uniparental isodisomy of chromosome 11p15

Haematologica, 2008
β-thalassemia major can be caused by homozygosity or compound heterozygosity for β-globin gene mutations (HBB gene). Most cases are inherited from parents who both have diseased alleles of the HBB gene.
Jan-Gowth Chang, Wen-Chan Tsai, Inn-Wen Chong, Chao-Sung Chang, Chyi-Chang Lin, Ta-Chih Liu   +5 more
doaj   +1 more source

Idiopathic Hypertriglyceridemia in Thalassemia Major: A Case Report [PDF]

National Journal of Laboratory Medicine, 2017
Thalassemia major is a severe hereditary haemolytic anaemia and is usually associated with normal serum lipid profile. But there are few reports in literature that hypertriglyceridemia can have an idiopathic association with β-thalassemia major.
Bhavya P Mohan, Prabhalekshmy KK, Letha V, Nisha TR   +3 more
doaj   +1 more source

Glycated Albumin as Marker for Early Hyperglycemia Detection in Adolescent with β Thalassemia Major

Indonesian Biomedical Journal, 2021
BACKGROUND: Hyperglycemia is one of the most common endocrine complications in children with β thalassemia major. Though the current diagnostic marker either requires fasting, has low reproducibility, or it is not an accurate for thalassemia patients ...
Dewinda Candrarukmi, Annang Giri Moelyo, Muhammad Riza   +2 more
doaj   +1 more source