Results 31 to 40 of about 4,949,451 (244)

Overview of the current issues and advances in haemopoietic stem cell transplantation for β-thalassemia major

Thalassemia Reports, 2011
Bone marrow transplantation (BMT) is the only possible curative treatment for β-thalassemia major. The largest experience occurred in Pesaro, Italy, where the BMT was applied after a standard risk assessment.
S.S. Anak
doaj   +1 more source

Relationship between Ferritin Levels with Calcium Levels in Patients Thalassemia β Major in Hospital in Jember

Journal of Agromedicine and Medical Sciences (AMS), 2023
Thalassemia β major is a hereditary disorder caused by mutations in the β-globin gene, which regulates the formation of one of the components that make up hemoglobin. This disorder results in the production of β-globin chains being reduced or not formed.
Fantya Cerebella Aslamy, Rini Riyanti, Cholis Abrori   +2 more
doaj   +1 more source

Prevalence of Depression in Patients with Thalassemia Major and Thalassemia Intermedia in Jahrom County [PDF]

تحقیق و توسعه سلامت, 2023
Introduction: Thalassemia is a common genetic blood disorder that is chronic and is associated with a wide range of serious psychological and clinical challenges, affecting an individual's psychological well-being similar to other chronic illnesses. This
Sara Matin, Mohsen Ghiasi, Navid Kalani, Ehsan Rahmanian   +3 more
doaj  

Hypertriglyceridemia in a Baby with Thalassemia Major

, 2020
Thalassemia is the most common inherited hemoglobin disorder around the world. It is usually associated with normal serum lipid profile. However, there are a few reports in literature that hypertriglyceridemia has an association with beta-thalassemia ...
Aditi Rawat, Poonam Agrawal, Saumya Pandey, Pratima Khare, Mrinal Gupta   +4 more
core   +1 more source

Pakistani children’s experiences of growing up with Beta-Thalassemia Major [PDF]

, 2015
In this study, we explored the lived experiences of children with beta-thalassemia major (β-TM). We considered children as experts on their experiences in contrast to the prevalent approach of asking parents or other adults about children’s perspectives.
Towell, A., Cartwright, T., Gul-E-Rana Mufti, Tony Towell, Tina Cartwright, Mufti, G.E.R.   +5 more
core   +1 more source

A Comparative Biochemical Study of Proteins Profile in Iraqi Children and Adolescent with ?-Thalassemia

Iraqi Journal of Pharmaceutical Sciences, 2017
The aim of the present research is to study different protein fractions in sera of children and adolescent with  β –thalassemia major and minor and to compare the results with that of healthy control.One hundred fifty children and adolescents were ...
Ali M. Malik, Emad M. Malik, Nawal MJ Al-Shammaa, Zeinab M. Al-Rubaei   +3 more
doaj   +3 more sources

Is There any Relationship Between the Repeated Complications of Sickle Cell Disease and the Potential Development of Acute Leukemia?

Oncology and Therapy
Sickle cell disease (SCD) is a severe monogenic hereditary hemoglobinopathy that is characterized by repeated clinical and biological manifestations able to generate stress erythopoiesis.
Giovanna Cannas, Mohamed Elhamri, Xavier Thomas   +2 more
doaj   +1 more source

The correlation between HLA class II and β-thalassemia major in Al-Karama teaching hospital

مجلة كلية الطب, 2016
Background: Thalassemia is a form of inherited autosomal recessive blood disorder characterized by abnormal formation of hemoglobin. Objective: Determine frequencies & association of HLA class II alleles (DRB1& DQB1) in Iraqi β-thalassemia major patients.
Sarmad M. Zeiny
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source