Determination of mutations in iron regulating genes of beta thalassemia major patients of Khyber Pakhtunkhwa, Pakistan [PDF]
Molecular Genetics & Genomic Medicine, 2020 Background Hepcidin and hemochromatosis (HFE) are iron regulatory proteins that are encoded by HAMP and HFE genes. Mutation in either HAMP gene or HFE gene causes Hepcidin protein deficiency that can lead to iron overload in beta thalassemia patients ...
Maryam Shah +7 more
doaj +2 more sources
Prevalence of Candida albicans in the oral cavity of Beta Thalassemia Major and Thalassemia Minor Patients [version 2; peer review: 2 approved] [PDF]
F1000ResearchAims To examine the correlation between iron, ferritin concentrations, and C. albicans infection in individuals with beta-thalassemia major and beta-thalassemia minor compared with healthy subjects.
Maha Adel Mahmood +1 more
doaj +2 more sources
Cutaneous Manifestations in Patients with Beta-Thalassemia Major. [PDF]
J Mother Child, 2023 Beta-thalassemia major is a transfusion-dependent thalassemia. Both ongoing disease-related inflammatory processes and chronic transfusions lead to iron overload, which is depicted by hyperferritinemia. We aimed to report the prevalence of various dermatological manifestations in beta-thalassemia major patients and their relationship with serum ...
Zulfiqar Z +6 more
europepmc +3 more sources
Heterozygous Beta Thalassemia in Parents of Children with Beta Thalassemia Major
Gomal Journal of Medical Sciences, 2004 Background: Beta thalassemia is the most common single gene disorder causing a major genetic health problem in the world. Beta thalassemia is common in Pakistan.
Imran-ud-Din Khattak +2 more
doaj +1 more source
Theorizing Beta Thalassemia Major: an Overview of Health Sociology [PDF]
RIMCIS, 2020 This research focuses on specific models of health and illness, explored by many researchers across the world. The sequential variations and critic of each model is summed up by researcher and the relevant theoretical orientations of beta thalassemia ...
Muhammad Abo ul Hassan Rashid +1 more
doaj +3 more sources
Genetic Study for Identifying Beta Thalassemia Trait in Relatives of Children with Beta Thalassemia Major. [PDF]
CureusThe most common inherited illness, thalassemia, is thought to have a detrimental effect on public health, particularly in endemic areas. Children with beta thalassemia disease have several mutations. Prevention and premarital examination are still the most effective measures to lessen the burden of beta thalassemia.This study primarily aimed to ...
Elasheer OM +5 more
europepmc +3 more sources
Hypoparathyroidism in Adult Patients with Beta-Thalassemia Major
Sultan Qaboos University Medical Journal, 2007 Objective: To evaluate the prevalence of hypoparathyroidism in adult transfusion-dependent patients with beta-thalassemia major in a teaching referral hospital in Oman.
Gihan Ali A M Sleem +2 more
doaj +3 more sources
Knowledge of Children and Adolescents with Beta Thalassemia Major about their Disease: An Assessment Study [PDF]
Egyptian Journal of Health Care, 2022 Background: Beta-thalassemia major is the most common hemoglobin disorder in the world. Assessing the knowledge of the children and adolescents regarding a beta- thalassemia major is important because helps to avoid complications.
Salma El Sayed Hassan +3 more
doaj +1 more source
The survival rate of patients with beta-thalassemia major and intermedia and its trends in recent years in Iran [PDF]
Epidemiology and Health, 2018 OBJECTIVES Thalassemia is a common genetic disease in Iran, especially in the north and south of Iran. The present study sought to determine the survival rate of patients with thalassemia in highly endemic regions of Iran and its variation in patients ...
Alireza Ansari-Moghaddam +4 more
doaj +1 more source