Results 21 to 30 of about 26,664 (228)

How early can myocardial iron overload occur in Beta thalassemia major? [PDF]

, 2014
BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
Gaohui Yang, Pan Hongfei, He, T, Lai, Y, Peng, P, Liu Rongrong, Long, X, Taigang He, Tan Shaohong, Liu, R, Hongfei Pan, Yang Weijia, Xingjiang Long, Rongrong Liu, Lai Yongrong, Yang Gaohui, He Taigang, Weijia Yang, Yang, G, Xinhua Zhang, Tan, S, Liling Long, Anderson Lisa, Lisa Anderson, Long Xingjiang, Yang, W, Zhang, X, Anderson, L, Peng Peng, Yongrong Lai, Zhang Xinhua, Long Liling, Pan, H, Shaohong Tan, Long, L   +34 more
core   +1 more source

Comparison of biochemical parameters of prevalent hemoglobinopathies with healthy individuals

Medicine Science, 2020
Thalassemia is the most frequently seen monogenetic disorders around the world that is inherited as a recessive single-gene disease, resulting from mutations in α-or β-globin gene clusters.
Emrah Yerlikaya, Hasan Karagecili, Mustafa Oguzhan Kaya   +2 more
doaj   +1 more source

Right ventricular volumes and function in thalassemia major patients in the absence of myocardial iron overload [PDF]

, 2010
Aim: We aimed to define reference ranges for right ventricular (RV) volumes, ejection fraction (EF) in thalassemia major patients (TM) without myocardial iron overload.Methods and results: RV volumes, EF and mass were measured in 80 TM patients who had ...
Maciej Garbowski, He, TG, Maceira, A, Francisco Alpendurada, Banya Winston, He, T, Taigang He, Carpenter, JP, Smith, GC, Kirk, P, Shah, F, Maceira Alicia, Porter, JB, John B Porter, Banya, W, He Taigang, Walker, JM, Kirk Paul, Alicia Maceira, Alpendurada Francisco, Gillian C Smith, Porter John B, Smith Gillian C, Farrukh Shah, Pennell, DJ, Shah Farrukh, Pennell Dudley J, Deac Monica, Dudley J Pennell, Alpendurada, F, Paul Kirk, Winston Banya, Carpenter John-Paul, John-Paul Carpenter, Deac, M, J Malcolm Walker, Garbowski, M, Walker J Malcolm, Garbowski Maciej, Monica Deac   +39 more
core   +1 more source

The Associations between HLA DQB1 different Alleles and β-thalassemia Major [PDF]

Minia Journal of Medical Research, 2020
Thalassemias are the commonest inherited hemoglobinopathies in the world. Approximately 68,000 children are born with various thalassemia syndromes each year. β-Thalassemia represents a major public health problem in Egypt. beta thalassemia. It is caused
Amel Kamal Eldin, ,Emad Abd El Naem, Mostafa Elsayed, Nada Zaki Mahmoud   +3 more
doaj   +1 more source

Newborn Screening Practices for Beta-Thalassemia in the United States

International Journal of Neonatal Screening, 2021
Beta-thalassemia, a heritable condition of abnormal hemoglobin production, is not a core condition on the United States Recommended Uniform Screening Panel (RUSP) for state and territorial newborn screening (NBS) programs.
Michael A. Bender, Mary Hulihan, Mary Christine Dorley, Maria del Pilar Aguinaga, Jelili Ojodu, Careema Yusuf   +5 more
doaj   +1 more source

Correlation of saliva characteristics and caries in beta-thalassemia major patients

Majalah Kedokteran Gigi Indonesia, 2021
A patient with beta-thalassemia major is known to have poor oral hygiene and a high risk of caries. Some studies showed that patients with beta-thalassemia have low salivary flow rate and acidic saliva.
Siti Rusdiana Puspa Dewi, Sherly Septhimoranie, Suryadi Muchzal   +2 more
doaj   +1 more source

Hematological Parameters in Beta Thalassemia Major Children [PDF]

Minia Journal of Medical Research, 2022
Background: Thalassemia is a hematological disorder that is caused by mutations in the genes that encode hemoglobin chains. Mutations in the β-globin gene are the most common cause of genetic disorders in humans, with 350 β-thalassemia variants ...
Zamzam Mohamed, Doaa Ismail, Samira Sayed, Arwa Aziz   +3 more
doaj   +1 more source

Pakistani children’s experiences of growing up with Beta-Thalassemia Major [PDF]

, 2015
In this study, we explored the lived experiences of children with beta-thalassemia major (β-TM). We considered children as experts on their experiences in contrast to the prevalent approach of asking parents or other adults about children’s perspectives.
Towell, A., Cartwright, T., Gul-E-Rana Mufti, Tony Towell, Tina Cartwright, Mufti, G.E.R.   +5 more
core   +1 more source

Current status of beta‐thalassemia and its treatment strategies

Molecular Genetics & Genomic Medicine, 2021
Background Thalassemia is an inherited hematological disorder categorized by a decrease or absence of one or more of the globin chains synthesis. Beta‐thalassemia is caused by one or more mutations in the beta‐globin gene.
Shaukat Ali, Shumaila Mumtaz, Hafiz Abdullah Shakir, Muhammad Khan, Hafiz Muhammad Tahir, Samaira Mumtaz, Tafail Akbar Mughal, Ali Hassan, Syed Akif Raza Kazmi, Sadia, Muhammad Irfan, Muhammad Adeeb Khan   +11 more
doaj   +1 more source

Thalassemia

Trends in Pediatrics, 2021
Defects in protein structure or synthesis of hemoglobin are called hemoglobinopathies. Thalassemia is the most common hemoglobinopathy, and it is estimated that 5% of the world population carries at least one variant allele of thalassemia.
Tekin Aksu, Sule Unal
doaj   +1 more source