Results 51 to 60 of about 4,949,451 (244)

Highlights on the Luspatercept Treatment in Thalassemia

open access: yes, 2023
Luspatercept has been shown to act as a ligand trap, selectively suppressing the deleterious effects of GDF11 that blocks terminal erythroid maturation, restoring normal erythroid differentiation and improving anemia in animal models of &beta ...
Yesim Aydinok, Aydinok, Yesim
core   +1 more source

A Comparative Study of Liver Function and Lipid Profile between Minor and Major Thalassemia Patient

open access: yesAl-SalamJournal for Medical Science
It is thought that only patients with major thalassemia need to be under healthy control compared to minor. Therefore, the purpose of this study is to compare the liver status complications of small thalassemia with those of major thalassemia. Therefore,
Assal Ghazi Alshammary   +2 more
doaj   +1 more source

THE CORRELATION OF β/α MRNA RATIO WITH CLINICAL AND HEMATOLOGICAL PARAMETERS IN PATIENTS WITH β-THALASSEMIA SYNDROME

open access: yesThe Iraqi Journal of Medical Sciences, 2022
Background: Thalassemias are a group of genetically transmitted blood diseases characterized by defects in the production of α- or β-chains of hemoglobin called α-thalassemia and β-thalassemia, respectively.
May H. Yousif, Hind S. Al-Mamoori
doaj   +1 more source

Thalassemia Major

open access: yesHematology/Oncology and Stem Cell Therapy, 2017
Thalassemia is the most common monogenic hematologic disease that affects millions in the world and kills thousands of patients every year. Without transfusion or transplantation, patients with thalassemia major are expected to die within months of diagnosis.
openaire   +2 more sources

Application of Machine Learning Approaches in Electrophoresis—A Comprehensive Review

open access: yesELECTROPHORESIS, EarlyView.
This review paper highlights key research on the applications of machine learning tools in electrophoresis. ABSTRACT The electrophoretic technique is widely used to analyze and purify charged molecules based on their size, shape, and charge using an electric field for various applications, including DNA fingerprinting, genetic research, disease ...
Umaeer Al Hammad   +2 more
wiley   +1 more source

Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia [PDF]

open access: yes, 2010
Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Pier Luigi Cocco   +7 more
core  

Watershed Infarct in Beta-Thalassemia Major Patient [PDF]

open access: yes, 2017
Background. The mechanism of stroke in beta-thalassemia was reported previously as cardioembolic and hypercoagulable state. However, there is no report of watershed infarct in beta-thalassemia anemia. Method.
Behnaz Ansari   +2 more
core   +1 more source

Mutational analysis of the Janus kinase II (V617F) gene in patients with β-Thalassemia major

open access: yesZanco Journal of Pure and Applied Sciences, 2020
β-Thalassemia is a group of congenital hemolytic anemia that characterized by the underproduction of the indispensable hemoglobin molecule, the oxygen and carbon dioxide carrying protein inside the red cells.
Salar Adnan Ahmed
doaj   +3 more sources

Descriptive Analysis of Epidemiology, Demographic Characteristics, and Survival of Dedifferentiated Liposarcoma in France

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Dedifferentiated liposarcoma (DDLPS) is a rare soft tissue sarcoma with limited real‐world epidemiologic data. This nationwide retrospective study describes the epidemiology, management, and outcomes of DDLPS in France using the NETSARC+ national sarcoma registry.
Julien Bollard   +23 more
wiley   +1 more source

Standardized T2* map of a normal human heart to correct T2* segmental artefacts; Myocardial iron overload and fibrosis in thalassemia intermedia versus thalassemia major patients and electrocardiogram changes in thalassemia major patients RID A-6953-2008

open access: yes, 2008
Studies of the standardized, 3D, 16-segments map of the circumferential distribution of T2* values, Of cardiovascular magnetic resonance (CMR) in thalassemia major (TM) and thalassemia intermedia (TI) patients and of electrocardiogram (ECG) changes ...
De Marchi D   +35 more
core   +1 more source

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