Results 51 to 60 of about 4,949,451 (244)
Highlights on the Luspatercept Treatment in Thalassemia
Luspatercept has been shown to act as a ligand trap, selectively suppressing the deleterious effects of GDF11 that blocks terminal erythroid maturation, restoring normal erythroid differentiation and improving anemia in animal models of &beta ...
Yesim Aydinok, Aydinok, Yesim
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A Comparative Study of Liver Function and Lipid Profile between Minor and Major Thalassemia Patient
It is thought that only patients with major thalassemia need to be under healthy control compared to minor. Therefore, the purpose of this study is to compare the liver status complications of small thalassemia with those of major thalassemia. Therefore,
Assal Ghazi Alshammary +2 more
doaj +1 more source
Background: Thalassemias are a group of genetically transmitted blood diseases characterized by defects in the production of α- or β-chains of hemoglobin called α-thalassemia and β-thalassemia, respectively.
May H. Yousif, Hind S. Al-Mamoori
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Thalassemia is the most common monogenic hematologic disease that affects millions in the world and kills thousands of patients every year. Without transfusion or transplantation, patients with thalassemia major are expected to die within months of diagnosis.
openaire +2 more sources
Application of Machine Learning Approaches in Electrophoresis—A Comprehensive Review
This review paper highlights key research on the applications of machine learning tools in electrophoresis. ABSTRACT The electrophoretic technique is widely used to analyze and purify charged molecules based on their size, shape, and charge using an electric field for various applications, including DNA fingerprinting, genetic research, disease ...
Umaeer Al Hammad +2 more
wiley +1 more source
Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia [PDF]
Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Pier Luigi Cocco +7 more
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Watershed Infarct in Beta-Thalassemia Major Patient [PDF]
Background. The mechanism of stroke in beta-thalassemia was reported previously as cardioembolic and hypercoagulable state. However, there is no report of watershed infarct in beta-thalassemia anemia. Method.
Behnaz Ansari +2 more
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Mutational analysis of the Janus kinase II (V617F) gene in patients with β-Thalassemia major
β-Thalassemia is a group of congenital hemolytic anemia that characterized by the underproduction of the indispensable hemoglobin molecule, the oxygen and carbon dioxide carrying protein inside the red cells.
Salar Adnan Ahmed
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ABSTRACT Dedifferentiated liposarcoma (DDLPS) is a rare soft tissue sarcoma with limited real‐world epidemiologic data. This nationwide retrospective study describes the epidemiology, management, and outcomes of DDLPS in France using the NETSARC+ national sarcoma registry.
Julien Bollard +23 more
wiley +1 more source
Studies of the standardized, 3D, 16-segments map of the circumferential distribution of T2* values, Of cardiovascular magnetic resonance (CMR) in thalassemia major (TM) and thalassemia intermedia (TI) patients and of electrocardiogram (ECG) changes ...
De Marchi D +35 more
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