Results 71 to 80 of about 71,330 (251)

Cardiac Complications in Thalassemia Major [PDF]

open access: yesHemoglobin, 2009
Thalassemia major is characterized by chronic ineffective erythropoiesis and anemia as its primary problems. These, in turn, produce physiologic adaptations in the cardiovascular system as well as pathologic/iatrogenic processes such as iron overload, splenectomy, nutritional deficiencies, chronic oxidative stress, and lung disease.
openaire   +2 more sources

Watershed Infarct in Beta-Thalassemia Major Patient [PDF]

open access: yes, 2017
Background. The mechanism of stroke in beta-thalassemia was reported previously as cardioembolic and hypercoagulable state. However, there is no report of watershed infarct in beta-thalassemia anemia. Method.
Behnaz Ansari   +2 more
core   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

open access: yesNeuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji   +4 more
wiley   +1 more source

Next‐Generation Paleopathology: Using Commercial AI in Bioarchaeological Diagnosis

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT Artificial intelligence encompasses computational systems capable of performing cognitive functions such as learning, reasoning, and problem‐solving. Within this domain, generative AI and large language models such as ChatGPT, Gemini, and Copilot have shown significant potential in clinical diagnostics.
Jessica Mongillo   +4 more
wiley   +1 more source

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

open access: yes
American Journal of Hematology, EarlyView.
Ferras Alashkar   +10 more
wiley   +1 more source

Warfare, Labor, and Urban Stress: Divergent Health Trajectories in Mongol‐Period Karakorum

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT This study examines major palaeopathological trends in Mongol‐period Karakorum and incorporates them into the existing body of research in order to deepen our understanding of health and survival, the impacts of conflict and violence on past populations, and the lived experiences of the city's diverse inhabitants within the broader socio ...
Júlia Olive‐Busom   +4 more
wiley   +1 more source

Evaluation of physical growth of Patient WithThalassemia Major Based on NCHS criteria [PDF]

open access: yes
Background: Beta thalassemia major, including the conditions in which the natural growth due to complications from those diseases can be disrupted. Despite the recent advances in treating these patients, growth retardation in a significant percentage of ...
آریش, گیتی   +4 more
core  

Diabetes mellitus in β-thalassemia major patients [PDF]

open access: yes, 2003
β-thalassemia major is a disease caused by β polypeptide chain synthesis disorder which is inherited as an autosomal recessive from both parents which is marked by little or no β globin chain synthesis.
Setiawan, Santy   +3 more
core   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij   +11 more
wiley   +1 more source

Effect of Assorted Globin Haplotypes and α-Thalassemia on the Clinical Heterogeneity of Hb S-β-Thalassemia [PDF]

open access: yes, 2019
Hemoglobinopathies and thalassemias are the most commonly encountered monogenic disorders of blood in humans, posing a major genetic and public health problem round the globe.
Kiran R. Kharat (686460)   +5 more
core   +1 more source

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