Results 61 to 70 of about 71,330 (251)
Evaluation of Hepatic Enzymes in major β-thalassemic Patients using Deferasirox
Iraqi Journal of Pharmaceutical Sciences, 2022 β-thalassemia major is a genetic disease that causes sever defect in normal hemoglobin synthesis. The patients with β-thalassemia major need periodic blood transfusions that can result in accumulation of body iron, so treatment with iron chelating agent ...
Ahmed Yahya Dallal Bashi +1 more
doaj +1 more source
Depression in mothers of children with thalassemia or blood malignancies: a study from Iran [PDF]
Background Several studies have found that parents of children with chronic diseases or disabilities have higher depression scores than control parents. Mothers usually take on the considerable part of the extra care and support that these children need
AliReza Farrokhi +9 more
core +1 more source
Bone Marrow Transplantation in Nonmalignant Haematological Diseases: What Have We Learned about Thalassemia? [PDF]
, 2023 Allogeneic stem cell transplantation remains the only therapy for congenital, severe haemoglobinopathies that is able to reverse the pathological phenotype. In the severe form of thalassemia, regular transfusions are needed early in life. This population
Luca Castagna +5 more
core +1 more source
Elevated Hemoglobin A2: A Molecular Revisited, and Implications to β‐Thalassemia Screening
Journal of Clinical Laboratory Analysis, EarlyView.In Thailand, the Hb A2 cut‐off value for β‐thalassemia carrier has been changed from 4.0% to 3.6% since 2015. We examined the molecular basis of β‐thalassemia in a large cohort of Thai subjects with this change. The molecular basis of β‐thalassemia was updated, and a change in the Hb A2 cut‐off can alter this spectrum.
Kritsada Singha +8 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.We evaluated the cfBEST assay for non‐invasive prenatal testing of α‐ and β‐thalassemia in 72 families. The assay correctly identified 88 of 93 fetal alleles, achieving an overall accuracy of 94.6%, a sensitivity of 94%, and a specificity of 95.35%, with 100% concordance with postnatal follow‐up.
Qin Liu +7 more
wiley +1 more source
Factors associated with continuing emergence of β-thalassemia major despite prenatal testing: a cross-sectional survey [PDF]
, 2017 Haleama Al Sabbah,1 Sarah Khan,1 Abdallah Hamadna,2 Lamia Abu Ghazaleh,2 Anwar Dudin,2 Bashar Adnan Karmi3 1College of Natural and Health Sciences, Zayed University, Dubai, UAE; 2Faculty of Medicine, An-Najah National University, Nablus, Palestine ...
Al Sabbah H +5 more
core
Cerebral Blood Transit in Sickle Cell Anemia
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Wesley T. Richerson +10 more
wiley +1 more source
Complications of patients with thalassemia major and intermedia in a selected Iranian population
Caspian Journal of Internal Medicine, 2022 Background: Due to anemia in thalassemia major (TM) and thalassemia intermedia (TI) patients, bone changes occur, especially in the broad bones like jaw and skull, which are the main sites of hematopoiesis.
Vahid Azizi +3 more
doaj
Movement Disorders Clinical Practice, EarlyView.Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider +3 more
wiley +1 more source
The Iraqi Journal of Medical Sciences, 2022 Background: Thalassemias are a group of genetically transmitted blood diseases characterized by defects in the production of ?- or ?-chains of hemoglobin called ?-thalassemia and ?-thalassemia, respectively.
May H. Yousif, Hind S. Al-Mamoori
doaj +4 more sources