Results 11 to 20 of about 71,330 (251)

Osteoporosis in Thalassemia Major [PDF]

Türk Osteoporoz Dergisi, 2012
Thalassemia Major is an inherited blood disorder which leads to ineffective erythropoiesis, bone marrow expansion, and skeletal deformity. In the last two decades the survival of the patients has improved considerably and osteoporosis has become a serious burden.
Pembe Hare Yiğitoğlu, Rengin Güzel
doaj   +4 more sources

Cholelithiasis in thalassemia major [PDF]

European Journal of Haematology, 2008
AbstractObjectives:  Aim of this study was to evaluate prevalence and characteristics of cholelithiasis in a large population of patients with thalassemia major (TM).Methods:  Data from 858 consecutive patients with transfusion‐dependent thalassemia at five major Italian centers were analyzed.
ORIGA, RAFFAELLA, Galanello R, Perseu L, Tavazzi D, Cappellini M, Terenzani L, Forni GL, Quarta G, Boetti T, Piga A.   +9 more
openaire   +6 more sources

Deferoxamine in Thalassemia Major [PDF]

New England Journal of Medicine, 1995
N ...
Splendiani G., Tozzo C., Mazzarella V., Casciani C. U., Lucarelli G., Angelucci E., Clift R., Cazzola M., Locatelli F., de Stefano P., Olivieri N. F., Nathan D. G., Cohen A. R.   +12 more
openaire   +3 more sources

Thalassemia Major [PDF]

Hematology/Oncology and Stem Cell Therapy, 2017
Thalassemia is the most common monogenic hematologic disease that affects millions in the world and kills thousands of patients every year. Without transfusion or transplantation, patients with thalassemia major are expected to die within months of diagnosis.
Said Y. Mohamed
openaire   +3 more sources

Transplantation for thalassemia major: alternative donors [PDF]

Current Opinion in Hematology, 2016
Purpose of review Lack of a human leukocyte antigen (HLA)-matched family donor is a major obstacle limiting the use of allogeneic hematopoietic stem cell transplantation (HSCT) to cure thalassemia major. Use of alternative donors, if found well tolerated enough, may be a viable option for transplantation in this setting ...
Locatelli F., Merli P., Strocchio L.
core   +8 more sources

Impact of Genetic Polymorphisms in Modifier Genes in Determining Fetal Hemoglobin Levels in Beta-Thalassemia [PDF]

, 2023
Genetic polymorphisms in Quantitative Trait Loci (QTL) genes such as BCL11A, HBS1L-MYB and KLF1 have been reported to influence fetal hemoglobin (HbF) levels.
Kausik Mandal, Poonam Tripathi, Aditya Narayan Sarangi, Anshul Gupta, Sarita Agarwal   +4 more
core   +1 more source

Development of the Quality of Life Questionnaire (SF-36) for Patients with β-Thalassemia Major and β-Thalassemia Intermedia Based on Extended Rasch Analysis [PDF]

, 2021
The quality of life (QoL) questionnaire (SF-36) contains 36 questions in eight subscales. It requires much time to fill in by the respondent. The objective of this study was to use Rasch models to develop a questionnaire that brings the desired outcome ...
Safizadeh, H, Sharifi, F, Bahrampour, A
core   +1 more source

Psychopathology in thalassemia major

Pediatrics International, 2009
AbstractBackground:  Thalassemia major (TM) is a chronic disease with adverse emotional effects on both the child and the family. The aim of this study was to investigate the psychiatric state and behavioral problems of children with TM.Methods:  Twenty children diagnosed with TM and 34 healthy children were enrolled in this study carried out by the ...
Polat, A., Çakaloz, Burcu, Çakaloz, İnanç, İnan, Murat, Oguzhanoglu, N.K.   +4 more
openaire   +6 more sources

How early can myocardial iron overload occur in Beta thalassemia major? [PDF]

, 2014
BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
Gaohui Yang, Pan Hongfei, He, T, Lai, Y, Peng, P, Liu Rongrong, Long, X, Taigang He, Tan Shaohong, Liu, R, Hongfei Pan, Yang Weijia, Xingjiang Long, Rongrong Liu, Lai Yongrong, Yang Gaohui, He Taigang, Weijia Yang, Yang, G, Xinhua Zhang, Tan, S, Liling Long, Anderson Lisa, Lisa Anderson, Long Xingjiang, Yang, W, Zhang, X, Anderson, L, Peng Peng, Yongrong Lai, Zhang Xinhua, Long Liling, Pan, H, Shaohong Tan, Long, L   +34 more
core   +1 more source

Right ventricular volumes and function in thalassemia major patients in the absence of myocardial iron overload [PDF]

, 2010
Aim: We aimed to define reference ranges for right ventricular (RV) volumes, ejection fraction (EF) in thalassemia major patients (TM) without myocardial iron overload.Methods and results: RV volumes, EF and mass were measured in 80 TM patients who had ...
Maciej Garbowski, He, TG, Maceira, A, Francisco Alpendurada, Banya Winston, He, T, Taigang He, Carpenter, JP, Smith, GC, Kirk, P, Shah, F, Maceira Alicia, Porter, JB, John B Porter, Banya, W, He Taigang, Walker, JM, Kirk Paul, Alicia Maceira, Alpendurada Francisco, Gillian C Smith, Porter John B, Smith Gillian C, Farrukh Shah, Pennell, DJ, Shah Farrukh, Pennell Dudley J, Deac Monica, Dudley J Pennell, Alpendurada, F, Paul Kirk, Winston Banya, Carpenter John-Paul, John-Paul Carpenter, Deac, M, J Malcolm Walker, Garbowski, M, Walker J Malcolm, Garbowski Maciej, Monica Deac   +39 more
core   +1 more source