Osteoporosis in Thalassemia Major
Türk Osteoporoz Dergisi, 2012 Thalassemia Major is an inherited blood disorder which leads to ineffective erythropoiesis, bone marrow expansion, and skeletal deformity. In the last two decades the survival of the patients has improved considerably and osteoporosis has become a serious burden.
Pembe Hare Yiğitoğlu, Rengin Güzel
doaj +4 more sources
Deferoxamine in Thalassemia Major
New England Journal of Medicine, 1995 N ...
Splendiani G. +12 more
openaire +3 more sources
Evaluation of Factors influencing the birth of Thalassemia in Family Members with Thalassemia Major in Southeast Iran in 2021 [PDF]
Journal of Advanced Biomedical Sciences, 2023 Background & Objectives: Beta-thalassemia is one of the complex diseases that causes many social and economic problems for the patient and his family. This study aimed to investigate factors influencing the birth of thalassemia (intermedia or major) in ...
Majid Naderi +5 more
doaj +1 more source
Knowledge of Children and Adolescents with Beta Thalassemia Major about their Disease: An Assessment Study [PDF]
Egyptian Journal of Health Care, 2022 Background: Beta-thalassemia major is the most common hemoglobin disorder in the world. Assessing the knowledge of the children and adolescents regarding a beta- thalassemia major is important because helps to avoid complications.
Salma El Sayed Hassan +3 more
doaj +1 more source
Major Thalassemia, Screening or Treatment: An Economic Evaluation Study in Iran [PDF]
International Journal of Health Policy and Management, 2022 BackgroundBeta-thalassemia minor and thalassemia major are an autosomal recessive disease with hypochromic, microcytic anemia, and morbidities, Today, therapeutic advances have significantly improved the life expectancy of thalassemia major patients, but
Firooz Esmaeilzadeh +4 more
doaj +1 more source
The Associations between HLA DQB1 different Alleles and β-thalassemia Major [PDF]
Minia Journal of Medical Research, 2020 Thalassemias are the commonest inherited hemoglobinopathies in the world. Approximately 68,000 children are born with various thalassemia syndromes each year. β-Thalassemia represents a major public health problem in Egypt. beta thalassemia. It is caused
Amel Kamal Eldin +3 more
doaj +1 more source
Changes in coagulation status in patients with β-thalassemia in Iraq: A case-control study
Medical Journal of Babylon, 2022 Background: The pathogenesis β-thalassemia is characterized by anemia resulting from reduced β-globin synthesis with low hemoglobin A (HbA) production and higher production of hemoglobin A2 (HbA2) and fetal hemoglobin (HbF).
Hussein Abdalzehra Wadaha +2 more
doaj +1 more source
Molecular Genetics & Genomic Medicine, 2020 Background Hepcidin and hemochromatosis (HFE) are iron regulatory proteins that are encoded by HAMP and HFE genes. Mutation in either HAMP gene or HFE gene causes Hepcidin protein deficiency that can lead to iron overload in beta thalassemia patients ...
Maryam Shah +7 more
doaj +1 more source
Evaluation of the Association of Transferrin Receptor Type 2 Gene Mutation (Y250X) with Iron Overload in Major β-Thalassemia [PDF]
Archives of Razi Institute, 2021 Thalassemia is an inherited blood disorder in which the body produces defective hemoglobin. One of the important processes to reduce the complication of major β-thalassemia is blood transfusion that leads to elevated ferritin levels in the blood.
J Abdulmalek Jaafar, N. A. M Al-Rashedi
doaj +1 more source
How early can myocardial iron overload occur in Beta thalassemia major? [PDF]
, 2014 BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
Gaohui Yang +34 more
core +2 more sources