Results 11 to 20 of about 71,295 (266)

Thalassemia Major

Hematology/Oncology and Stem Cell Therapy, 2017
Thalassemia is the most common monogenic hematologic disease that affects millions in the world and kills thousands of patients every year. Without transfusion or transplantation, patients with thalassemia major are expected to die within months of diagnosis.
Said Y. Mohamed
openaire   +3 more sources

Role of red blood cells “annexin V” and platelets “P-selectin” in patients with thalassemia

Hematology/Oncology and Stem Cell Therapy, 2019
Objective/Background: Certain hemostatic anomalies found in patients with thalassemia suggest the existence of a chronic hypercoagulable state. Several etiologic factors may play a role in the pathogenesis of the hypercoagulable state in those patients ...
Zahraa Najah Mahdi, Subh S. Al-Mudallal, Bassam M. Hameed   +2 more
doaj   +1 more source

Multi-center transferability of a breath-hold T2 technique for myocardial iron assessment. [PDF]

, 2008
Background: Cardiac iron overload is the leading cause of death in thalassemia major and is usually assessed using myocardial T2* measurements. Recently a cardiovascular magnetic resonance (CMR) breath-hold T2 sequence has been developed as a possible ...
Tan, RS, Tan Ru, Chan, G.C.F, He, T, Fogel Mark A, Firmin David N, Au, W-Y, Pennell, Dudley J., Chan, GCF, Fogel, MA, Lam, W.M, Aydinok, Y, Chu, WCW, He, Taigang, Cohen, AR, Ng, I, Chu Winnie CW, Cohen, Alan R., Pennell, DJ, Pennell Dudley J, Firmin, D.N, Chu, W.C.W, Biceroglu, S, Fogel, M.A, Tan, R.S, Lam, WM, Chan Godfrey CF, Lam Wynnie M, Firmin, David N., Biceroglu Selen, Aydinok Yesim, Aydinok, Yesim, Firmin, DN, Kirk, Paul, Fogel, Mark A., Pennell, D.J, Ng Ivy, Kirk, P, Au, Wing-Yan, Tan, Ru San, Au, WY, He Taigang, Kirk Paul, Chan, GC, Biceroglu, Selen, Cohen, A.R, Au Wing-Yan, Chu, Winnie C. W., Chu, WC, Au, W.-Y, Lam, Wynnie M., Cohen Alan R, Ng, Ivy, Chan, Godfrey C. F.   +53 more
core   +1 more source

Beta-Thalassemia major and pregnancy

Bratislava Medical Journal, 2013
It was studied the clinical management and the medical outcomes of 6 pregnancies in 5 women affected by Beta Thalassemia major, based on last guidelines and pharmacological treatments.Paediatric Department and Department of Obstetrics and Gynaecology of the University of Catania.These patients were taken among a group of 116 women affected by beta ...
Gulino F. A., Vitale S. G., Fauzia M., Cianci S., Pafumi C., Palumbo M. A.   +5 more
openaire   +8 more sources

Clinical Course of COVID-19 in a Thalassemia Major Patient who Underwent Haematopoietic Stem Cell Transplantation

Bezmiâlem Science, 2021
We herein reported the course of Coronavirus diasease-19 (COVID-19) in a 21-year-old patient with thalassemia majo rdisease. The patient who underwent haematopoietic stem cell transplantation in 2013 and developed alloimmunization, presented with high ...
Aziz Ahmad HAMİDİ, Yıldız ULU, Habibullah AKTAŞ   +2 more
doaj   +1 more source

Relationship between Ferritin Levels with Calcium Levels in Patients Thalassemia β Major in Hospital in Jember

Journal of Agromedicine and Medical Sciences (AMS), 2023
Thalassemia β major is a hereditary disorder caused by mutations in the β-globin gene, which regulates the formation of one of the components that make up hemoglobin. This disorder results in the production of β-globin chains being reduced or not formed.
Fantya Cerebella Aslamy, Rini Riyanti, Cholis Abrori   +2 more
doaj   +1 more source

A Comparative Biochemical Study of Proteins Profile in Iraqi Children and Adolescent with ?-Thalassemia

Iraqi Journal of Pharmaceutical Sciences, 2017
The aim of the present research is to study different protein fractions in sera of children and adolescent with  β –thalassemia major and minor and to compare the results with that of healthy control.One hundred fifty children and adolescents were ...
Ali M. Malik, Emad M. Malik, Nawal MJ Al-Shammaa, Zeinab M. Al-Rubaei   +3 more
doaj   +3 more sources

Assessment of level of Awareness regarding Thalassemia Major among Parents of Affected Children

Journal of Rawalpindi Medical College, 2021
Background: Thalassemia major is amongst the most common genetic disorders in developing countries like Pakistan. This research project aims to assess the level of knowledge among people related to thalassemia and the number of thalassemia cases linked ...
Faizan Fazal, Mateen Arshad, Haris Mustafa, Muhammad Ebad Ur Rehman, Usama Tanveer, Sidra Hamid   +5 more
doaj   +1 more source

Pakistani children’s experiences of growing up with Beta-Thalassemia Major [PDF]

, 2015
In this study, we explored the lived experiences of children with beta-thalassemia major (β-TM). We considered children as experts on their experiences in contrast to the prevalent approach of asking parents or other adults about children’s perspectives.
Towell, A., Cartwright, T., Gul-E-Rana Mufti, Tony Towell, Tina Cartwright, Mufti, G.E.R.   +5 more
core   +1 more source

Impact of Genetic Polymorphisms in Modifier Genes in Determining Fetal Hemoglobin Levels in Beta-Thalassemia

, 2023
Genetic polymorphisms in Quantitative Trait Loci (QTL) genes such as BCL11A, HBS1L-MYB and KLF1 have been reported to influence fetal hemoglobin (HbF) levels.
Kausik Mandal, Poonam Tripathi, Aditya Narayan Sarangi, Anshul Gupta, Sarita Agarwal   +4 more
core   +1 more source