Results 31 to 40 of about 25,953 (267)

Single‐Injection Multi‐Omics Analysis by Direct Infusion Mass Spectrometry

Angewandte Chemie, EarlyView.
A high‐throughput direct infusion mass spectrometry platform, enabled by gas‐phase ion mobility separation, supports single‐injection analysis of peptides, polar metabolites, and lipids. Coupled with custom software, it identified ∽1,300 proteins and ∽600 metabolites in ∽4.3 minutes per sample, and demonstrated broad utility in macrophage polarization ...
Yuming Jiang, Ivan Salladay‐Perez, Amanda Momenzadeh, Jesús Muñoz‐Estrada, Uktarsh Tripathi, Anthony J. Covarrubias, Jesse G. Meyer   +6 more
wiley   +2 more sources

Designing Deferoxamine-Loaded Flaxseed Gum and Carrageenan-Based Controlled Release Biocomposite Hydrogel Films for Wound Healing

Gels, 2022
In this study, biocomposite hydrogel films made from flaxseed gum (FSG)/kappa carrageenan (CGN) were fabricated, using potassium chloride as a crosslinker and glycerol as a plasticizer.
Tayyaba Sadiq, Syed Haroon Khalid, Ikram Ullah Khan, Hira Mahmood, Sajid Asghar   +4 more
doaj   +1 more source

Comparison of deferasirox and deferoxamine effects on iron overload and immunological changes in patients with blood transfusion-dependent β-thalassemia

Asian Journal of Transfusion Science, 2017
Introduction: Beta-thalassemias are a cluster of inherited (autosomal recessive) hematological disorders prevalent in the Mediterranean area due to defects in synthesis of β chains of hemoglobin.
Hayder M Al-Kuraishy, Ali I Al-Gareeb
doaj   +1 more source

Effect of deferiprone or deferoxamine on right ventricular function in thalassemia major patients with myocardial iron overload [PDF]

, 2011
Background Thalassaemia major (TM) patients need regular blood transfusions that lead to accumulation of iron and death from heart failure. Deferiprone has been reported to be superior to deferoxamine for the removal of cardiac iron and improvement in ...
Antonio Piga, Athanassios Aessopos, Dudley J Pennell, Efstathios D Gotsis, Francisco Alpendurada, Gillian C Smith, John Carpenter, Mark A Tanner, Mark A Westwood, Markissia Karagiorga, Michael Roughton, Mohammed H Alam, Renzo Galanello, Vasili Berdoukas, Vasili Ladis   +14 more
core   +4 more sources

Deferoxamine retinopathy: spectral domain-optical coherence tomography findings [PDF]

, 2014
BACKGROUND: To describe the spectral domain optical coherence tomography (SD-OCT) findings of a patient who developed pigmentary retinopathy following high-dose deferoxamine administration.
Chao-Ping Yang, Cheng-Hsiu Wu, Chi-Chun Lai, Wei-Chi Wu, Yi-Hsing Chen   +4 more
core   +1 more source

The regulatory mechanism of deferoxamine spray in promoting the healing of chronic wounds in third-degree burns

Yixue xinzhi zazhi
Objective To explore the effects and its mechanism of deferoxamine spray on the healing process of chronic wounds from third-degree burns. Methods Screening the concentration of deferoxamine spray suitable for subsequent experiments through ...
CHAI Langjie, LI Qin, GUO Liang, HUANG Jianglong   +3 more
doaj   +1 more source

Iron Neurotoxicity and Protection by Deferoxamine in Intracerebral Hemorrhage

Frontiers in Molecular Neuroscience, 2022
Intracerebral hemorrhage (ICH) is a subtype of stroke that is characterized by high morbidity and mortality, for which clinical outcome remains poor. An extensive literature indicates that the release of ferrous iron from ruptured erythrocytes in the ...
Zhe Li, Zhe Li, Zhe Li, Yang Liu, Yang Liu, Yang Liu, Ruixue Wei, Ruixue Wei, Ruixue Wei, Suliman Khan, Suliman Khan, Suliman Khan, Ruiyi Zhang, Ruiyi Zhang, Ruiyi Zhang, Yan Zhang, Yan Zhang, Yan Zhang, Voon Wee Yong, Mengzhou Xue, Mengzhou Xue, Mengzhou Xue   +21 more
doaj   +1 more source

Comparative efficacy of deferiprone, deferoxamine and combination of deferiprone and deferoxamine on serum ferritin value in Beta-Thalassemia patients [PDF]

, 2015
Background: Iron overload is a predictable and life-threatening complication in patients with thalassemia. Effective and convenient iron chelation remains one of the main targets of clinical management of thalassemia major.
Amlashi, H.M., Behnampour, N., Jahazi, A., Mirbehbahani, N.   +3 more
core   +1 more source

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss

Advanced Science, EarlyView.
 . ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao, Xiang Li, Yaqi Liao, Liman Liu, Xian Gao, Hailiang Lin, Wenli Ni, Huawei Li, Yan Chen, Wenyan Li   +9 more
wiley   +1 more source

Deferoxamine-Based Materials and Sensors for Fe(III) Detection

Chemosensors, 2022
Deferoxamine (DFO) is a siderophore widely studied for its ability to bind iron(III) strongly. Thanks to its versatility, it is suitable for several clinical and analytical applications, from the recognized iron(III) chelation therapy to the most recent ...
Giancarla Alberti, Camilla Zanoni, Lisa Rita Magnaghi, Raffaela Biesuz   +3 more
doaj   +1 more source