Results 31 to 40 of about 16,985 (220)

Efficacy of intramuscular and intraperitoneal deferoxamine for aluminum chelation [PDF]

, 1987
Efficacy of intramuscular and intraperitoneal deferoxamine for aluminum chelation. As intravenous administration of deferoxamine is difficult in home dialysis patients we set out to determine the efficacy of intramuscular (i.m.) and intraperitoneal (i.p.)
Hasbargen, James A., Miller, Nancy L., Alfrey, Allen C., Molitoris, Bruce A., Alfrey, Patricia S., Kaehney, William D., Smith, Barbara J.   +6 more
core   +1 more source

Iron Effects on Clostridioides difficile Toxin Production and Antimicrobial Susceptibilities

Antibiotics, 2022
Despite the benefits of red blood cell (RBC) transfusion therapy, it can render patients vulnerable to iron overload. The excess iron deposits in various body tissues cause severe complications and organ damage such as cardiotoxicity and mold infections.
Jason Yamaki, Swati Chawla, Shirley Tong, Kate Alison Lozada, Sun Yang   +4 more
doaj   +1 more source

INHIBITION OF PROLIFERATION OF HUMAN-LEUKEMIC CELL-POPULATIONS BY DEFEROXAMINE [PDF]

, 1986
Deferoxamine is a hydroxylamine which binds ferric ions to form a highly stable complex. Since iron is thought to be required at a critical stage for cell proliferation, we investigated the effect of deferoxamine on the proliferative activity of human ...
L. VILLA, E. POLLI, A. MAIOLO, L. LOMBARDI, P. FOA   +4 more
core   +1 more source

N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson’s Disease

Antioxidants, 2020
Oxidative stress is a key mediator in the development and progression of Parkinson’s disease (PD). The antioxidant N-acetylcysteine (NAC) has generated interest as a disease-modifying therapy for PD but is limited due to poor bioavailability, a short ...
Leah Mursaleen, Brendon Noble, Stefanie Ho Yi Chan, Satyanarayana Somavarapu, Mohammed Gulrez Zariwala   +4 more
doaj   +1 more source

How to Improve the Antioxidant Defense in Asphyxiated Newborns—Lessons from Animal Models

Antioxidants, 2020
Oxygen free radicals have been implicated in brain damage after neonatal asphyxia. In the early phase of asphyxia/reoxygenation, changes in antioxidant enzyme activity play a pivotal role in switching on and off the cascade of events that can kill the ...
Hanna Kletkiewicz, Maciej Klimiuk, Alina Woźniak, Celestyna Mila-Kierzenkowska, Karol Dokladny, Justyna Rogalska   +5 more
doaj   +1 more source

Acute renal failure following deferoxamine overdose [PDF]

, 2003
A 17-year-old patient with sickle cell-beta thalassemia undergoing treatment with home iron chelation therapy inadvertently received ten times the recommended dose of intravenous deferoxamine. Acute renal failure (ARF) developed within hours.
Flynn, Joseph T., Prasannan, Latha, Levine, John E.   +2 more
core   +1 more source

Designing Deferoxamine-Loaded Flaxseed Gum and Carrageenan-Based Controlled Release Biocomposite Hydrogel Films for Wound Healing

Gels, 2022
In this study, biocomposite hydrogel films made from flaxseed gum (FSG)/kappa carrageenan (CGN) were fabricated, using potassium chloride as a crosslinker and glycerol as a plasticizer.
Tayyaba Sadiq, Syed Haroon Khalid, Ikram Ullah Khan, Hira Mahmood, Sajid Asghar   +4 more
doaj   +1 more source

Comparison of deferasirox and deferoxamine effects on iron overload and immunological changes in patients with blood transfusion-dependent β-thalassemia

Asian Journal of Transfusion Science, 2017
Introduction: Beta-thalassemias are a cluster of inherited (autosomal recessive) hematological disorders prevalent in the Mediterranean area due to defects in synthesis of β chains of hemoglobin.
Hayder M Al-Kuraishy, Ali I Al-Gareeb
doaj   +1 more source

Deferoxamine effect on the delay phenomenon [PDF]

, 2021
Tıpta UzmanlıkRekonstrüksiyon başarısını ve flep yaşayabilirliğini arttırmak amacıyla bir çok cerrahi teknik ve ilaç denenmiştir. Deferoksaminin yeni damar oluşumunu arttırdığı ve yara iyileşmesine olumlu katkısının olduğu bilinmekle beraber cerrahi ...
Erdem, Ufuk
core  

The regulatory mechanism of deferoxamine spray in promoting the healing of chronic wounds in third-degree burns

Yixue xinzhi zazhi
Objective To explore the effects and its mechanism of deferoxamine spray on the healing process of chronic wounds from third-degree burns. Methods Screening the concentration of deferoxamine spray suitable for subsequent experiments through ...
CHAI Langjie, LI Qin, GUO Liang, HUANG Jianglong   +3 more
doaj   +1 more source