Results 11 to 20 of about 25,953 (267)

Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress. [PDF]

, 2018
The transmembrane protein neuropilin-1 (NRP1) promotes vascular endothelial growth factor (VEGF) and extracellular matrix signaling in endothelial cells (ECs).
Bosseboeuf, E, Chikh, A, De Winter, N, Dufton, N, Gestri, G, Issitt, T, Raimondi, C, Randi, AM, Senatore, V   +8 more
core   +3 more sources

Iron overload and iron chelating agent exposure in anemia-associated outer retinal degeneration: a case report and review of the literature

BMC Ophthalmology, 2021
Background Deferoxamine retinopathy is the informally designated term used to describe a characteristic pattern of outer retinal degeneration in iron-overloaded chronic anemia patients who are treated with deferoxamine. We hypothesize that insufficiently
Mohamed Belmouhand, Christina Eckmann-Hansen, Tomas Ilginis, Eva Birgitte Leinøe, Bo Kok Mortensen, Michael Larsen   +5 more
doaj   +1 more source

Effect of Deferoxamine on Rat Fetal Bone Formation and on it is Certain Regulating Genes

Kufa Journal for Veterinary Medical Sciences, 2021
The aim of this study is to investigate the deferoxamine effect on rat fetal bone formation and on certain regulating genes expression that play a vital key role in bone formation.
Abeer Esmael Thanoon , Ali Saeed Alchalabi   +1 more
doaj   +1 more source

How early can myocardial iron overload occur in Beta thalassemia major? [PDF]

, 2014
BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
A Aessopos, AM Maceira, AW Leung, B Modell, B Modell, B Modell, BA Davis, C Borgna-Pignatti, DH Fitchett, DJ Weatherall, DT Kremastinos, F Alpendurada, G Barosi, Gaohui Yang, GM Brittenham, GM Brittenham, HF Pan, Hongfei Pan, JC Wood, JC Wood, JC Wood, JL Fernandes, K Tziomalos, Liling Long, Lisa Anderson, LJ Anderson, LJ Anderson, M Angastiniotis, M Bejaoui, M Westwood, MA Aldouri, MA Tanner, MA Tanner, MA Tanner, MAEM Engle, NF Olivieri, P Kirk, Peng Peng, Q Meng, Rongrong Liu, Shaohong Tan, T He, Taigang He, V Positano, Weijia Yang, Xiaolei Xu, Xingjiang Long, Xinhua Zhang, Yong-rong Lai, Yongrong Lai   +49 more
core   +2 more sources

Wnt5a is a key target for the pro-osteogenic effects of iron chelation on osteoblast progenitors

Haematologica, 2016
Iron overload due to hemochromatosis or chronic blood transfusions has been associated with the development of osteoporosis. However, the impact of changes in iron homeostasis on osteoblast functions and the underlying mechanisms are poorly defined ...
Ulrike Baschant, Martina Rauner, Ekaterina Balaian, Heike Weidner, Antonella Roetto, Uwe Platzbecker, Lorenz C. Hofbauer   +6 more
doaj   +1 more source

Antibacterial and Angiogenic Poly(ionic liquid) Hydrogels

Gels, 2022
Wounds, particularly under low-hydration conditions, require more time to repair successfully. Therefore, there is an urgent need to develop wound dressings that can accelerate wound healing.
Chengju Sheng, Xuemei Tan, Qing Huang, Kewen Li, Chao Zhou, Mingming Guo   +5 more
doaj   +1 more source

DEVELOPMENT OF AN ANALYTICAL METHOD FOR THE DETERMINATION OF LEAD BASED ON LOCAL SURFACE PLASMON RESONANCE OF SILVER NANOPARTICLES [PDF]

Química Nova, 2020
Lead is environmental pollutant that even in low trace is harmful for human health and wildlife. In this study we presented a colorimetric method for determination of Pb2+ in water by aggregation of silver nanoparticles capped citrate in the presence of ...
Hamed Azimi, Seyyed Hamid Ahmadi, Mohammadreza Manafi, Syed Husain Hashemi Mousavi, Mostafa Najafi   +4 more
doaj   +1 more source

Use of single-chain antibody derivatives for targeted drug delivery [PDF]

, 2016
Single-chain antibodies (scFvs), which contain only the variable domains of full-length antibodies, are relatively small molecules that can be used for selective drug delivery.
Ahmadzadeh, V., Erfani-Moghadam, V., Jaliani, H.Z., Khalili, M., Safdari, Y., Zarei, V.   +5 more
core   +1 more source

Deferoxamine Compensates for Decreases in B Cell Counts and Reduces Mortality in Enterovirus 71-Infected Mice

Marine Drugs, 2014
Enterovirus 71 is one of the major causative agents of hand, foot and mouth disease in children under six years of age. No vaccine or antiviral therapy is currently available.
Yajun Yang, Jing Ma, Jinghui Xiu, Lin Bai, Feifei Guan, Li Zhang, Jiangning Liu, Lianfeng Zhang   +7 more
doaj   +1 more source

Improved nuclear localization of DNA-binding polyamides [PDF]

, 2006
Regulation of endogenous genes by DNA-binding polyamides requires effective nuclear localization. Previous work employing confocal microscopy to study uptake of fluorophore-labeled polyamides has demonstrated the difficulty of predicting a priori the ...
Baird, Belitsky, Belitsky, Best, Bianchi, Claire S. Jacobs, Crowley, Dervan, Dervan, Dervan, Dickinson, Dudouet, Edelson, Foister, Gottesfeld, Juliano, Kaizerman, Kielkopf, Kong, Michelle E. Farkas, Nguyen-Hackley, Nicholas G. Nickols, Olenyuk, Peter B. Dervan, Suto, Trauger, Ueda, Vandyke, White, Wood, Wurtz   +30 more
core   +3 more sources