Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. [PDF]
OBJECTIVE: The authors have conjugated chelating agents (DOTA and NODAGA) with a peptide (pituitary adenylate cyclase-activating peptide [PACAP] analogue) that has a high affinity for VPAC1 receptors expressed on cancer cells.
Chen, Chang-Po +6 more
core +2 more sources
Iron chelating agents for iron overload diseases
Although iron is an essential element for life, an excessive amount may become extremely toxic both for its ability to generate reactive oxygen species, and for the lack in humans of regulatory mechanisms for iron excretion.
Guido Crisponi +2 more
doaj +1 more source
On-line preconcentration using dual mini-columns for the speciation of chromium(III) and chromium(VI) and its application to water samples as studied by inductively coupled plasma-atomic emission spectrometry [PDF]
On-line preconcentration system for the selective, sensitive and simultaneous determination of chromium species was investigated. Dual minicolumns containing chelating resin were utilized for the speciation and preconcentration of Cr(III) and Cr(VI) in ...
Hamada, Kazuhide +5 more
core +1 more source
Chelators as Antineuroblastomas Agents
Neuroblastoma represents 8-10 % of all malignant tumors in childhood and is responsible for 15 % of cancer deaths in the pediatric population. Aggressive neuroblastomas are often resistant to chemotherapy. Canonically, neuroblastomas can be classified according to the MYCN (N-myc proto-oncogene protein) gene amplification, a common marker of tumor ...
C W, D'Acunto +5 more
openaire +2 more sources
Designing organometallic compounds for catalysis and therapy [PDF]
Bioorganometallic chemistry is a rapidly developing area of research. In recent years organometallic compounds have provided a rich platform for the design of effective catalysts, e.g. for olefin metathesis and transfer hydrogenation.
Abraha Habtemariam +188 more
core +1 more source
Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Bailey H. H. +67 more
core +1 more source
The brain has a unique biological complexity and is responsible for important functions in the human body, such as the command of cognitive and motor functions.
T. A. Sales +6 more
semanticscholar +1 more source
The effect of using deinked mixed office waste pulp on the properties of Alkaline Proxide Mechanical Pulp from cotton stalk [PDF]
The present study was carried out aiming to investigate the effect of using Deinked Mixed Office Waste Pulp (MOW) on the properties of Alkaline Peroxide Mechanical Pulp (APMP) from cotton stalk.
Mehrnoosh Tavakoli +3 more
doaj +1 more source
Unusual DNA binding modes for metal anticancer complexes [PDF]
DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
core +1 more source
Metal Ions, Metal Chelators and Metal Chelating Assay as Antioxidant Method
Heavy metals are essential for a wide range of biological processes, including the growth and reproduction of cells, synthesis of biomolecules, many enzymatic reactions, and the body’s immunity, but their excessive intake is harmful.
I. Gulcin, S. Alwasel
semanticscholar +1 more source

