Results 141 to 150 of about 4,372,191 (364)

BBN and the Primordial Abundances

open access: yes, 2005
The relic abundances of the light elements synthesized during the first few minutes of the evolution of the Universe provide unique probes of cosmology and the building blocks for stellar and galactic chemical evolution, while also enabling constraints ...
C. Chiappini   +21 more
core   +2 more sources

Rapid Chemical Enrichment by Intermittent Star Formation in GN-z11

open access: yesThe Astrophysical Journal Letters
We interpret the peculiar supersolar nitrogen abundance recently reported by the James Webb Space Telescope observations for GN-z11 ( z = 10.6) using our state-of-the-art chemical evolution models.
Chiaki Kobayashi, Andrea Ferrara
doaj   +1 more source

STELLAR CHEMICAL ABUNDANCES: IN PURSUIT OF THE HIGHEST ACHIEVABLE PRECISION [PDF]

open access: yes, 2014
The achievable level of precision on photospheric abundances of stars is a major limiting factor on investigations of exoplanet host star characteristics, the chemical histories of star clusters, and the evolution of the Milky Way and other galaxies ...
M. Bedell   +5 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Chemical Abundances in Star-Forming Galaxies at High Redshift

open access: yes, 2009
A galaxy's metallicity provides a record of star formation, gas accretion, and gas outflow, and is therefore one of the most informative measurements that can be made at high redshift. It is also one of the most difficult. I review methods of determining
Dawn K. Erb   +4 more
core   +1 more source

The High-Redshift Gas-Phase Mass–Metallicity Relation in FIRE-2

open access: yesThe Astrophysical Journal Letters
The unprecedented infrared spectroscopic capabilities of JWST have provided high-quality interstellar medium metallicity measurements and enabled characterization of the gas-phase mass–metallicity relation (MZR) for galaxies at z ≳ 5 for the first time ...
Andrew Marszewski   +4 more
doaj   +1 more source

Chemical Abundances and the Hierarchical Clustering

open access: yes, 2003
to appear in Recycling intergalactic and intersetellar matter, IAUSS Vol 217 ...
Tissera, Patricia B., Lambas, Diego G.
openaire   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The nature of Long-GRB host galaxies from chemical abundances

open access: yes, 2010
Gamma-ray bursts (GRBs) are the most energetic events after the Big Bang and they have been observed up to very high redshift. By means of measures of chemical abundances now available for the galaxies hosting such events,thought to originate from the ...
Akerman   +76 more
core   +1 more source

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