Results 131 to 140 of about 84,685 (303)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Noble Gas Planetology and the Xenon Clouds of Uranus

The Planetary Science Journal
Noble gases provide tracers of cosmic provenance that are accessible to a future Uranus atmospheric probe. Argon and krypton are expected to be well mixed on Uranus with respect to H _2 and He, although condensation at the winter pole may be possible ...
Kevin Zahnle
doaj   +1 more source

Initial abundances generator; allows choices of chemical mixture and network

, 2019
<p>MESA work directory associated with an initial abundances generator; allows choices of chemical mixture and network</p> <p> </p ...
Ostrowski, Jakub (6530606), Ostrowski, Jakub   +1 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A Catalogue of Planetary Nebulae Chemical Abundances in the Galactic Bulge [PDF]

In this, the third of a series of papers, we present well determined chemical abundances for 124 Planetary nebulae (PNe) in the Galactic bulge from deep, long-slit FORS2 spectra from the 8.2 m ESO Very Large telescope (VLT). Prior to this work there were
Parker, Quentin A., Rees, Bryan, Zijlstra, Albert A.; id_orcid, Tan, Shuyu   +3 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

New Neutral–Neutral Pathways in the Chemistry of Silicon- and Sulfur-bearing Molecules in the Cold Interstellar Medium

The Astrophysical Journal
Silicon is the most abundant third-row element in space and plays a major role in interstellar dust as silicate particles. Furthermore, silicon is important for the formation of silicate dust in oxygen-rich AGB stars and in supernova remnants.
Samuel F. M. Costa, Márcio O. Alves, Sérgio Pilling, Jing Li, Breno R. L. Galvão   +4 more
doaj   +1 more source

The GALAH survey: Improving chemical abundances using star clusters

Large spectroscopic surveys aim to consistently compute stellar parameters of very diverse stars, while minimizing systematic errors. We explore the use of stellar clusters as benchmarks to verify the precision of spectroscopic parameters in the fourth ...
Buder, Sven, Beeson, Kevin L., Daniel B. Zucker, Freeman, Ken, Gayandhi M. De Silva, Bland-Hawthorn, Joss, Kevin L. Beeson, Gary S. Da Costa, D'Orazi, Valentina, Dennis Stello, Madeline Howell, Zwitter, Tomaz, Michael Hayden, Tomaž Zwitter, Traven, Gregor, Sharma, Sanjib, Thomas Nordlander, Sven Buder, Nordlander, Thomas, Janez Kos, Sarah L. Martell, Zucker, Daniel B., Ken Freeman, De Grijs, Richard, Stello, Dennis, Da Costa, Gary S., De Silva, Gayandhi M., Siddhartha Saikia, Lind, Karin, Kos, Janez, Joss Bland-Hawthorn, Karin Lind, Martell, Sarah L., McKenzie, Madeleine, Richard de Grijs, Madeleine McKenzie, Gregor Traven, Hayden, Michael, Sanjib Sharma, Howell, Madeline, Geraint F. Lewis, Lewis, Geraint F., Valentina D’Orazi, Saikia, Siddhartha   +43 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Gaia FGK benchmark stars: Spectral library and abundances of α and Fe-peak elements of the third version

Astronomy & Astrophysics
Context. Accurate determination of the chemical abundances in stars plays a pivotal role in understanding stellar structure and evolution, nucleosynthesis, and the chemical enrichment history of the Milky Way.
Casamiquela L., Soubiran C., Jofré P., Vitali S., Blanco-Cuaresma S., Lagarde N., Slumstrup D., Heiter U., Palmerio J. T., Brouillet N., Elgueta S., Rojas–Arriagada A., Aguilera–Gómez C., Hernández–Araya I., Creevey O. L., Balaguer–Núñez L., Carrera R.   +16 more
doaj   +1 more source