Results 111 to 120 of about 5,445,983 (296)

A Systematic NLTE Study of Very Metal-poor Stars with Metallicity Down to −4.3 dex. II. Lithium Abundance and New Insight of the Lithium Plateau

The Astrophysical Journal
Metal-poor stars are crucially important for understanding the early Galaxy, first stars, and the Universe. In this series of papers, we present a homogeneous non–local thermodynamic equilibrium (NLTE) abundance analysis of 12 elements for 103 very metal-
Hong-Liang Yan, Jinxiao Qin, Shuai Liu, Zeming Zhou, Gang Zhao, Jianrong Shi, Sofya Alexeeva, Huawei Zhang, Haining Li, Huiling Chen, Junbo Zhang, Yufu Shen, Wako Aoki, Tadafumi Matsuno, Jingkun Zhao   +14 more
doaj   +1 more source

The Open Cluster Chemical Abundances from Spanish Observatories survey (OCCASO) [PDF]

, 2015
We present the motivation, design and current status of the Open Cluster Chemical Abundances from Spanish Observatories survey (OCCASO). Using the high resolution spectroscopic facilities available at Spanish observatories, OCCASO will derive chemical ...
Jordi, C., Martínez-Vázquez, C. E., CARRERA, JIMENEZ RICARDO JESUS, Allende-Prieto, C., PANCINO, ELENA, del Pino, A., Casamiquela, L., Balaguer-Núñez, L., Recio-Blanco, A., Blanco-Cuaresma, S., Murabito, S., Gallart, C., Aparicio, A.   +12 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The High-Redshift Gas-Phase Mass–Metallicity Relation in FIRE-2

The Astrophysical Journal Letters
The unprecedented infrared spectroscopic capabilities of JWST have provided high-quality interstellar medium metallicity measurements and enabled characterization of the gas-phase mass–metallicity relation (MZR) for galaxies at z ≳ 5 for the first time ...
Andrew Marszewski, Guochao Sun, Claude-André Faucher-Giguère, Christopher C. Hayward, Robert Feldmann   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Recalibration of the Hα Surface Brightness–Radius Relation for Planetary Nebulae Using Gaia DR3: New Distances and the Milky Way Oxygen Radial Gradient

The Astrophysical Journal
The spatial distribution of chemical elements in the Galactic disk provides key constraints on models of galaxy evolution. However, studies using planetary nebulae (PNe) as tracers have been historically limited by large uncertainties in their distances.
Oscar Cavichia, Hektor Monteiro, Miguel Cerviño, Adalberto R. da Cunha-Silva, Walter J. Maciel, André F. S. Cardoso   +5 more
doaj   +1 more source

Gaia FGK benchmark stars

Astronomy & Astrophysics
Context. In the current era, in which an unprecedented wealth of data are available for the study of the Milky Way, Gaia benchmark stars (GBSs) have become an established reference and calibration sample. Studies of stellar structure and evolution and of
Vitali S., Jofré P., Casamiquela L., Soubiran C., Heiter U., Aguilera-Gómez C., Barrios-López D., Blanco-Cuaresma S., Escorza A., Hernández-Araya I., Signor T., Sinclair-Wentworth H., Worley C.   +12 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Actinide-boost Star LAMOST J122216.85–063345.2: A Detailed r-process Abundance Study with Gemini-S/GHOST

The Astrophysical Journal
We present a detailed chemical-abundance analysis of an actinide-boost ( $\mathrm{log}\epsilon $ (Th/Dy) = –0.74) star, LAMOST J122216.85–063345.2 (J1222), a very metal-poor ([Fe/H] = –2.45) halo star with moderate enhancement in rapid neutron-capture ...
Miji Jeong, Young Sun Lee, Vinicius M. Placco, Yutaka Hirai, Timothy C. Beers, Jeong-Eun Heo, Kristin Chiboucas, Emily Deibert, Roberto Gamen, Venu M. Kalari, Eder Martioli, Ruben Diaz, Manuel Gomez- Jimenez, Roque Ruiz-Carmona, Greg Burley, J. Gordon Robertson, Kathleen Labrie, Joanna Thomas-Osip   +17 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source