Results 161 to 170 of about 4,372,191 (364)
The Impact of Initial Composition on Massive Star Evolution and Nucleosynthesis
We study the sensitivity of presupernova evolution and supernova nucleosynthesis yields of massive stars to variations of the initial composition. We use the solar abundances from Lodders, and compute two different sets of initial stellar compositions ...
Christopher West+4 more
doaj +1 more source
CHEMICAL IMPRINTS IN ATMOSPHERIC ABUNDANCES IN PLANET- HOSTING STARS
We examined 12 planet-hosting stars based on homogeneous spectral data (obtained with the SOPHIE echelle spectrograph with R = 75,000 at the OHP, France) and using uniform techniques for determination of parameters and abundances of a series of elements (
T. Mishenina, N. Basak, V. Kovtyukh
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
The observed chemical diversity of Milky Way stars places important constraints on Galactic chemical evolution and the mixing processes that operate within the interstellar medium. Recent works have found that the chemical diversity of disk stars is low.
Catherine Manea+5 more
doaj +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
The Chemical Abundances of the Halo Clusters of the Galaxy [PDF]
R. Canterna, R. A. Schommer
openalex +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Complete Survey of r-process Conditions: The (Un)robustness of the r-process(es)
Heavy elements are synthesized by the r -process in neutron star mergers and potentially in rare supernovae linked to strong magnetic fields. Expensive hydrodynamic simulations of these extreme environments are usually postprocessed to calculate the ...
Jan Kuske+2 more
doaj +1 more source
Density Distribution and Chemical Abundances in NGC 7027 [PDF]
Andrea Preite-Martinez, Nino Panagiat
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source