Results 191 to 200 of about 4,406,721 (399)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Figuring Out Gas and Galaxies In Enzo (FOGGIE). VIII. Complex and Stochastic Metallicity Gradients at z > 2

open access: yesThe Astrophysical Journal
Gas-phase metallicity gradients are a crucial element in understanding the chemical evolution of galaxies. We use the FOGGIE simulations to study the metallicity gradients (∇ Z ) of six Milky Way–like galaxies throughout their evolution.
Ayan Acharyya   +9 more
doaj   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

A Photoionization Model for the Infrared Coronal Line Emission in the Classical Nova V1716 Scorpii

open access: yesThe Astrophysical Journal
A near-infrared spectrum of nova V1716 Scorpii (PNV J17224490-4137160), a recent bright ( ${V}_{\max }=7.3$ mag), Fermi-LAT detected γ -ray source, was modeled using the photoionization code CLOUDY.
C. E. Woodward   +4 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Determining Stellar Elemental Abundances from DESI Spectra with the Data-driven Payne

open access: yesThe Astrophysical Journal Supplement Series
Stellar abundances for a large number of stars provide key information for the study of Galactic formation history. Large spectroscopic surveys such as the Dark Energy Spectroscopic Instrument (DESI) and LAMOST take median-to-low-resolution ( R ≲ 5000 ...
Meng Zhang   +10 more
doaj   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Chemical Abundance Calibrations for the Narrow-Line Region of Active Galaxies [PDF]

open access: bronze, 1998
Thaisa Storchi‐Bergmann   +3 more
openalex   +1 more source

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