Results 191 to 200 of about 4,473,250 (366)
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Analysis of the Internal Radial Gradient of Chemical Abundances in Spiral Galaxies from CALIFA
The Astrophysical JournalThe study of chemical evolution is of paramount importance for understanding the evolution of galaxies. Models and observations propose an inside-out mechanism in the formation of spiral galaxy disks, implying a negative radial gradient of elemental ...
A. F. S. Cardoso +3 more
doaj +1 more source
HII Regions And the Protosolar Helium, Carbon, and Oxygen Abundances in the Context of Galactic Chemical Evolution [PDF]
, 2010 Leticia Carigi, M. Peimbert
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Chemical Abundances in SFG and DLA
, 2005 We investigate the chemical abundances of local star-forming galaxies which cause Damped Lyman Alpha lines. A metallicity versus redshift diagram is constructed, on which the chemical abundances of low-redshift star-forming galaxy populations are compared with those of high-redshift Damped Lyman Alpha systems.
Schulte-Ladbeck, Regina E. +2 more
openaire +2 more sources
The population of planetary nebulae near the Galactic Centre: chemical abundances [PDF]
, 2017 O. Cavichia +3 more
openalex +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The Astrophysical JournalGrouping stars by chemical similarity has the potential to reveal the Milky Way’s evolutionary history. The APOGEE stellar spectroscopic survey has the resolution and sensitivity for this task.
Catherine Manea +11 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The Sunburst Arc with JWST. III. An Abundance of Direct Chemical Abundances
The Astrophysical JournalAbstract We measure the gas-phase abundances of the elements He, N, O, Ne, S, Ar, and Fe in an individual H ii region known to be leaking Lyman-continuum photons in the Sunburst Arc, a highly magnified galaxy at redshift z = 2.37. We detect the temperature-sensitive auroral lines [S ii] λλ4070, 4076, [O iii] λ4363, [S ...
Brian Welch +13 more
openaire +3 more sources