Results 201 to 210 of about 5,445,983 (296)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Global distribution of deep-sea natural products shows environmental and phylogenetic undersampling with potential for biodiscovery. [PDF]

Sci Rep
Harris LM, Preet G, Desai R, Hasan AH, Vad J, Bribiesca-Contreras G, Astakala RV, Glover AG, Jaspars M, Copley J.   +9 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Modified Starch Flooding in Carbonates: Impact on Oil Recovery and Crude Oil Composition. [PDF]

ACS Omega
de Araujo LLGC, Sodré LGP, Mitze Muller Franco D, Cescon LDS, Gontijo B, Da Cruz GF.   +5 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

The COVID-19 pandemic influenced the temporal dynamics of antimicrobial resistance markers and bacterial community across urban wastewater treatment plants. [PDF]

Braz J Microbiol
Filho CGB, Oliveira FAS, Rodrigues VLM, Hissa DC, Barros MVH, de Farias AA, Dantas GT, Dos Santos AB, Ximenes JCM, Melo VMM.   +9 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Multi-omic characterization of microbial dynamics during spontaneous fermentation of sweet wine Picolit variety. [PDF]

Front Microbiol
Dell'Alma M, Cesana M, Kenny P, Peron G, Cafarella C, Rigano F, Mondello L, Mangieri N, Pizzi S, Russo P, Mora D, Gargari G.   +11 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Enhanced In Vivo Antinociceptive Activity and GC-MS Chemical Profiling of In Vitro-Grown <i>Acmella radicans</i> Plants Elicited with <i>Rhizopus microsporus</i>. [PDF]

Molecules
Hernández-Aubert G, Montiel-Ruiz RM, Hurtado-Díaz I, Silva-Guzmán JA, Torres-Rendón JG, Manríquez-González R, Cruz-Sosa F, Bernabé-Antonio A.   +7 more
europepmc   +1 more source