Results 161 to 170 of about 852,367 (264)

Chemical Activation of a Single Melamine Molecule via Isomerization Followed by Metalation with a Copper Atom. [PDF]

ACS Nano
Rothe K, Alkorta M, Néel N, Frederiksen T, Kröger J.   +4 more
europepmc   +1 more source

Chemical activation of SAT1 corrects diet-induced metabolic syndrome. [PDF]

Cell Death Differ, 2020
Castoldi F, Hyvönen MT, Durand S, Aprahamian F, Sauvat A, Malik SA, Baracco EE, Vacchelli E, Opolon P, Signolle N, Lefevre D, Bossut N, Eisenberg T, Dammbrueck C, Pendl T, Kremer M, Lachkar S, Einer C, Michalke B, Zischka H, Madeo F, Keinänen TA, Maiuri MC, Pietrocola F, Kroemer G.   +24 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Machine Learning-Based Prediction of the Adsorption Characteristics of Biochar from Waste Wood by Chemical Activation. [PDF]

Materials (Basel)
Chang J, Lee JY.
europepmc   +1 more source

Novel Methodologies for Chemical Activation in Organic Synthesis under Solvent-Free Reaction Conditions. [PDF]

Molecules, 2020
Avila-Ortiz CG, Juaristi E.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Chemical Activation Boosted Interface Interaction between Poly(tetrafluoroethylene-co-hexafluoropropylene) Film and Silver Coating. [PDF]

Polymers (Basel)
Wang H, Guo X, Li X, Gong C, Zhao Y.
europepmc   +1 more source

Chemical Activation of Forage Grass-Derived Biochar for Treatment of Aqueous Antibiotic Sulfamethoxazole. [PDF]

ACS Omega, 2020
Zeng S, Kan E.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

A Strategy for Modeling Nonstatistical Reactivity Effects: Combining Chemical Activation Estimates with a Vibrational Relaxation Model. [PDF]

J Chem Theory Comput
Rožić T, Teynor MS, Došlić N, Leitner DM, Solomon GC.   +4 more
europepmc   +1 more source