Results 101 to 110 of about 16,837,088 (341)
Recent Advances in the Application of Natural Coagulants for Sustainable Water Purification
EngGrowing pressure from shrinking freshwater supplies and worsening pollution has heightened the demand for more effective water treatment solutions, especially those that promote reuse.
Davide Frumento, Ştefan Ţălu
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Effects of Chemical Weapons on Cancer Development in Human
Kurdistan Journal of Applied Research, 2016 Although use of chemical weapons has low probability, it can cause a large scale casualties among exposed people if it is used. These kind of weapons have been used by human being since ancient history.
Belal A. Muhammad
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Disposing of chemical weapons safely [PDF]
From World War I to 1968, the United States produced chemical weapons as a deterrent against use of simi- lar weapons by other countries. Though never used in battle, these U.S. weapons are now obsolete and deteriorating with age.
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Defesa química: histórico, classificação dos agentes de guerra e ação dos neurotóxicos
Química Nova, 2012 Chemical agents are substances used for their toxic effects on humans, animals and plants. The main objective of chemical defense is to develop systems that reduce these effects while minimizing impact on the operational capacity of military troops.
Gustavo Rocha Silva +3 more
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
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Integrated Management of Clubroot in Zhejiang Province, China
AgronomyClubroot, caused by Plasmodiophora brassicae, is a destructive soil-borne disease significantly harming global Brassica crop production. This study employed the Williams and European Clubroot Differential (ECD) and Williams systems to identify the ...
Yi Zhang +8 more
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
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