Results 171 to 180 of about 7,423,179 (348)

Residual decontamination chemical agents negatively affect adhesion and proliferation of osteoblast-like cells on implant surface. [PDF]

Int J Implant Dent, 2020
Balderrama ÍF, Cardoso MV, Stuani VT, Oliveira RC, Matos AA, Greghi SLA, Sant'Ana ACP.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Chemical warfare agents

Continuing Education in Anaesthesia Critical Care & Pain, 2006
James Geoghegan, Jeffrey L Tong
openaire   +1 more source

ACEGEN: Reinforcement Learning of Generative Chemical Agents for Drug Discovery. [PDF]

J Chem Inf Model
Bou A, Thomas M, Dittert S, Navarro C, Majewski M, Wang Y, Patel S, Tresadern G, Ahmad M, Moens V, Sherman W, Sciabola S, De Fabritiis G.   +12 more
europepmc   +1 more source

New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections. [PDF]

RSC Med Chem, 2020
Suslov EV, Mozhaytsev ES, Korchagina DV, Bormotov NI, Yarovaya OI, Volcho KP, Serova OA, Agafonov AP, Maksyutov RA, Shishkina LN, Salakhutdinov NF.   +10 more
europepmc   +1 more source

Efficacy of adjunctive anti-plaque chemical agents in managing gingivitis: a systematic review and meta-analysis.

Journal of Clinical Periodontology, 2015
J. Serrano, M. Escribano, S. Roldán, Conchita Martín, D. Herrera   +4 more
semanticscholar   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Editorial: Metals in medicine

Frontiers in Chemistry, 2022
Zhe Liu, Christian Hartinger, Nora Kulak
doaj   +1 more source

Environmental and Occupational Exposure to Chemical Agents and Health Challenges I-What Message Can Bring to Regulatory Science? [PDF]

Toxics
Ladeira C.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source