Results 51 to 60 of about 16,837,088 (341)
Management of Chemical Terrorism and Chemical Disasters
International Journal of Disaster Management, 2021 Though the possibility of terrorist groups obtaining chemical weapons and inflicting mass destruction is relatively low, the relevance of chemical agents remains high since the use of such chemical agents in causing potentially dangerous consequences ...
Kannan Gajendran Balachandar
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Towards AI Research Agents in the Chemical Sciences [PDF]
An underlying problem shared by experimental scientists is to achieve optimal behavior of their systems and arrive at new discoveries while searching over an array of controls.
Ofer, Shir
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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Journal of Association of Pulmonologist of Tamil NaduBackground: Pleurodesis alleviates symptoms such as dyspnea, chest pain, cough and prevents recurrent pleural collections which require repeated thoracentesis. Pleurodesis improves the quality of life as a minimally invasive procedure.
Venkateshwaran Kathamuthu +3 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Diagnosis of exposure to chemical warfare agents: An essential tool to counteract chemical terrorism
, 2009 Methods to analyze chemical warfare agents (CW-agents) and their decomposition products in environmental samples were developed over the last decades. In contrast herewith, procedures for analysis in biological samples have only recently been developed ...
Noort, D. +3 more
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A systematic review of p53 regulation of oxidative stress in skeletal muscle
Redox Report, 2018 Background: p53 is a tumor suppressor protein involved in regulating a wide array of signaling pathways. The role of p53 in the cell is determined by the type of imposed oxidative stress, its intensity and duration.
Kaitlyn Beyfuss, David A. Hood
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
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Acta Scientiarum Polonorum: Hortorum Cultus, 2016 The objective of our studies was to develop effective, chemical methods of protecting narrow-leaved lavender (Lavandula angustifolia) against Phytophthora citrophthora with regard to their application.
Mirosław Korzeniowski +4 more
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