Results 71 to 80 of about 16,837,088 (341)

Introduction to chemical warfare agents, relevant simulants and modern neutralisation methods.

open access: yesOrganic and biomolecular chemistry, 2019
Despite international prohibition, some ill-intentioned states and organisations have shown their will and capacity to run chemical weapon programs, and the number of incidents involving chemical warfare agents (CWA) has significantly increased in recent
Baptiste Picard   +3 more
semanticscholar   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

The Evolution of Phosphotriesterase for Decontamination and Detoxification of Organophosphorus Chemical Warfare Agents

open access: yesChemico-Biological Interactions, 2019
The organophosphorus chemical warfare agents were initially synthesized in the 1930’s and are some of the most toxic compounds ever discovered. The standard means of decontamination are either harsh chemical hydrolysis or high temperature incineration ...
Andrew N. Bigley, F. Raushel
semanticscholar   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Exogenous Crosslinking of Tendons as a Strategy for Mechanical Augmentation and Repair: A Narrative Review

open access: yesOrthopedic Research and Reviews, 2023
Alexandru Fofiu,1,2 Robert G Tripon,3 Tiberiu Băţagă,4 Traian V Chirilă2,5– 8 1Department of Orthopedics-Traumatology, Emergency County Hospital Bistriţa, Bistriţa Năsăud, Romania; 2School of ...
Fofiu A   +3 more
doaj  

Salts of Therapeutic Agents: Chemical, Physicochemical, and Biological Considerations

open access: yesMolecules, 2018
The physicochemical and biological properties of active pharmaceutical ingredients (APIs) are greatly affected by their salt forms. The choice of a particular salt formulation is based on numerous factors such as API chemistry, intended dosage form ...
Deepak Gupta   +4 more
semanticscholar   +1 more source

SENSOR ARRAY ABLE TO DETECT AND RECOGNISE CHEMICAL WARFARE AGENTS [PDF]

open access: yes
In this paper we studied a device based on array of six different sensors with surface acoustic wave for detections and recognition of three chemical warfare agents (chloropicrin, soman and lewisite).
S. Serban   +7 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Chemical burns of gingiva and its management

open access: yesSRM Journal of Research in Dental Sciences, 2018
Chemical burns on the gingiva can be caused by the use of certain pharmaceutical and nonpharmaceutical products by patients or by injudicious use of caustics by the dental clinician. These lesions in the oral cavity, however, are rarely reported.
M M Dayakar   +4 more
doaj   +1 more source

Chemical agents : instructions for shipping blood specimens to CDC after a chemical exposure incident [PDF]

open access: yes
Guidance in Accordance with Packaging Instructions International Air Transport Authority (IATA) 650 Biological Substance Category B. See "Chemical Agents: Shipping Instructions for Specimens Collected from People who May Have Been Exposed to Chemical ...

core  

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