Results 201 to 210 of about 1,063,418 (267)

Chemical Analyses of Interlaboratory Standards

, 1980
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Low-Dose H₂O₂ Priming Improves Performance Under Simulated Marine Heatwave Conditions in a Coastal Bivalve. [PDF]

Glob Chall
Mascitelli C, Monticelli G, Nardi A, Rovere GD, Rilievo G, Bernardini I, Macrì N, Cesaroni D, Tavolazzi V, Andreatta G, Patarnello T, Bargelloni L, Peruzza L, Benedetti M, Milan M.   +14 more
europepmc   +1 more source

Global Bias-Aware Synthesis of Meta-Analyses Reveals Agroforestry's Potential for Improving Soil Health. [PDF]

Glob Chang Biol
Camille Manon R, Damien B, Margret K, Johan S, Florian W, Andrea S, Sonja K.   +6 more
europepmc   +1 more source

Sharply Contrasting Chemotypes Coincide with Aggression and Divergence in Cryptic African Carpenter Ant Populations. [PDF]

J Chem Ecol
Pohl M, Laukamp T, Caspers M, Paczkowski S, Buellesbach J.   +4 more
europepmc   +1 more source

Structures of protein folding intermediates on the ribosome. [PDF]

Nat Struct Mol Biol
Chan SHS, Streit JO, Włodarski T, Mitropoulou AN, Cassaignau AME, Bukvin IV, Waudby CA, Cabrita LD, Christodoulou J.   +8 more
europepmc   +1 more source

Medicinal Amazonian Oleoresins: An Eco-Friendly Chemical Fingerprinting Method. [PDF]

Plants (Basel)
Ribeiro R, Carneiro GRA, Pereira HMG, Padilha MC, Veiga-Junior VF.   +4 more
europepmc   +1 more source

Repositioning Natural Products in Modern Drug Discovery: Technological Innovation, Systems Pharmacology, and Pathological Validation. [PDF]

Int J Mol Sci
Nakadate K, Ito N, Kawakami K.
europepmc   +1 more source

Cultivar to chemotype: characterizing complex botanicals with mass spectrometry metabolomics.

Nat Prod Rep
Kellogg JJ, Jordan RT, Ranaweera MM, Custer K, Anez SG, Bendlin J, Chacon FT, Chen X.   +7 more
europepmc   +1 more source