Assessment of Homologous Recombination System Gene Expression in Chemologically Induced Carcinogenesis In Vivo Models. [PDF]
Tsyganov MM +9 more
europepmc +1 more source
The role of constitutive nitric‐oxide synthase in regulation of IKKα after ultraviolet irradiation
cNOS enhances IKKα expression following UVB exposure by promoting promoter activation, transcriptional elongation, and Ets‐1 stabilization. These actions sustain IKKα levels, reduce UV‐induced skin carcinogenesis, and highlight cNOS as a key protective factor against solar UV damage.
Yuxi Zhou +6 more
wiley +1 more source
Loss of the translational repressor 4E-BP1 promotes skin carcinogenesis. [PDF]
Zhou Y +5 more
europepmc +1 more source
Effects of solar‐simulated (UVB plus UVA) radiation on the skin microbiome: An exploratory study
This exploratory in vivo study investigated the effects of solar‐simulated ultraviolet radiation (UVB plus UVA) on the human skin microbiome. Healthy male volunteers were exposed to suberythemal and erythemal UV doses, and skin microbiota were analyzed at multiple time points using flow cytometry‐based profiling and the open‐access bioinformatic ...
Florian Dimmers +8 more
wiley +1 more source
Toxicogenomic Characterization of Perfluorooctanoic Acid-Associated Bladder Carcinogenesis. [PDF]
Liu Y, Tang A, Wang H.
europepmc +1 more source
Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes
Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto +8 more
wiley +1 more source
Core targets of bisphenol A in cervical cancer revealed by network toxicology and molecular docking. [PDF]
Li Y +6 more
europepmc +1 more source
Abstract Space exploration involves many dangers including galactic cosmic radiation (GCR). This class of radiation includes high‐energy protons and heavy ionizing ions. NASA has defined GCR as a carcinogenic risk for long‐duration space missions. To date, no clear strategy has been developed to counter chronic GCR exposure.
Siena Edwards +3 more
wiley +1 more source
Immature squamous metaplastic epithelium of Weber's glandular duct: a significant origin of HPV-independent oropharyngeal squamous cell carcinoma in the base of the tongue. [PDF]
Chen X +7 more
europepmc +1 more source

