Results 251 to 260 of about 176,623 (273)
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Cancer, 1975
The field of chemical carcinogenesis is reviewed, with emphasis on three aspects: 1) environmental chemicals are a major cause of human cancer; 2) most chemical carcinogens require metabolic activation by mixed-function oxidases to electrophilic metabolites that form strong covalent chemical bonds with cellular macromolecules and thereby initiate the ...
Thomas H. Maugh, Jean L. Marx
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The field of chemical carcinogenesis is reviewed, with emphasis on three aspects: 1) environmental chemicals are a major cause of human cancer; 2) most chemical carcinogens require metabolic activation by mixed-function oxidases to electrophilic metabolites that form strong covalent chemical bonds with cellular macromolecules and thereby initiate the ...
Thomas H. Maugh, Jean L. Marx
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ENVIRONMENTAL CHEMICAL CARCINOGENESIS
Medical Journal of Australia, 1978The methodology of revealing and studying chemical carcinogens in the environment is based on epidemiology, animal testing, and short-term laboratory studies. The techniques and limitations of these respective investigations are described. From evidence of carcinogenicity, extrapolation must be made to assess whether a particular substance is a cause ...
B W, Stewart, G A, Sarfaty
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Clinics in Dermatology, 1989
Abstract The purpose of this review is to update clinical dermatologists about current concepts of chemical carcinogenesis in skin. The incidence of skin cancer is increasing steadily and it has been estimated that of all new cancers diagnosed annually in the United States, almost one third originate in the skin.
H, Mukhtar, H F, Merk, M, Athar
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Abstract The purpose of this review is to update clinical dermatologists about current concepts of chemical carcinogenesis in skin. The incidence of skin cancer is increasing steadily and it has been estimated that of all new cancers diagnosed annually in the United States, almost one third originate in the skin.
H, Mukhtar, H F, Merk, M, Athar
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Revista espanola de oncologia, 1985
The author reviews the chemical carcinogenesis mechanisms at the level of the interaction between the carcinogenic agents and the informative molecules, proteins and nucleic acids.
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The author reviews the chemical carcinogenesis mechanisms at the level of the interaction between the carcinogenic agents and the informative molecules, proteins and nucleic acids.
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Cutaneous chemical carcinogenesis
Journal of the American Academy of Dermatology, 1986This review is designed to inform the clinician of current concepts regarding the pathogenesis of chemically induced skin cancer. Chemicals induce cutaneous cancers in a wide variety of experimental animals and in humans. The most common benign experimental tumors are papillomas and keratoacanthomas, whereas common malignancies are squamous cell ...
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