Results 131 to 140 of about 360,654 (257)

Chemical composition of manganese nodules from the Southern Ocean

open access: yes, 1976
Chemical composition of manganese nodules from the Southern Ocean using wet chemical analysis ...
Goodell, H G   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Photochemical Phosphorus-Hydrogen-Oxygen Network for Hydrogen-dominated Exoplanet Atmospheres

open access: yesThe Astrophysical Journal
Due to the detection of phosphine (PH _3 ) in the solar system gas giants Jupiter and Saturn, PH _3 has long been suggested to be detectable in exosolar substellar atmospheres too.
Elspeth K. H. Lee   +5 more
doaj   +1 more source

Chemical Composition, FTIR Studies and Antibacterial Activity of Passiflora edulis f. edulis (Fruit)

open access: yes, 2019
Because of the strong interest in the use of bio-products as alternatives to chemically derived antibiotics or antimicrobial agents, passion fruits extracts were evaluated for their antibacterial activity and chemical composition.
Humaira Rizwana   +2 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Chemical composition and biological evaluation of traditional algerian plants Melissa officinalis L. and Urtica dioica L.

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry
Melissa officinalis L. and Urtica dioica L. were investigated for their phytochemical profiles as well as their antioxidant and anti-lithiatic properties. LC-MS/MS analysis revealed that M.
Dahia Meridja   +4 more
doaj   +1 more source

Chemical composition of ocean manganese nodules using Neutron activation analysis (previously unpublished, published online 2016)

open access: yes, 1965
Chemical composition of ocean manganese nodules using X-ray fluorescence analysis (XRF) (previously unpublished, published online ...
John L Mero (6959513), Mero, John L
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Extraction, Chemical Composition and Antidiabetic Potential of Crude Polysaccharides from Centella asiatica (L.) Urban

open access: yesPolish Journal of Food and Nutrition Sciences
The global prevalence of diabetes mellitus (DM) is escalating, posing a significant challenge to human healthcare systems. In the present study, mineral and monosaccharide compositions, and antidiabetic potential of polysaccharide fractions separated ...
Meng Li   +8 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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