Results 131 to 140 of about 621,408 (312)

Using EGA-GC to Analyze Nicotine N-oxide in Order to Explain Low Nicotine Concentrations in E-cigarette Liquids [PDF]

, 2018
Evolved-gas analysis coupled with gas chromatography (EGA-GC) was used to analyze e-cigarette liquids. Previous analyses of e-cigarette liquids have shown that the determined concentration of nicotine is lower than the advertised concentration.
Wuerch, Cory
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Theoretical studies of radiation effects in composite materials for space use [PDF]

Tetraglycidyl 4,4'-diamino diphenyl methane epoxy cured with diamino diphenyl sulfone was used as a model compound. Computer programs were developed to calculate (1) energy deposition coefficients of protons and electrons of various energies at different
Chang, C. K., Kamaratos, E.
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Quantitative health risk assessment of respiratory exposure to 1,3-Butadiene in a petrochemical industry

Salāmat-i kār-i Īrān, 2020
Background and aims: In recent decades, air quality in different work environments has been a major concern. It is clear that the chemical materials used in industries have a profound effect on the quality of workplace air.
mohsen sadeghi yarandi, ali karimi, ali asghar sajedian, vahid ahmadi, farideh golbabaei   +4 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Assessing Bioconcentration and Biotransformation of BDE-47 In Vitro: The Relevance of Bioavailable and Intracellular Concentrations

Journal of Xenobiotics
The development of alternative methods that link cellular and predictive toxicity to high-level toxicity is a key focus of current research within the framework of the 3Rs in animal experimentation.
Paloma De Oro-Carretero, Jon Sanz-Landaluze   +1 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Evaluación de la exposición ocupacional a solventes en trabajadores de una fábrica de calzado

Revista Cubana de Higiene y Epidemiología, 1999
Se efectuó un estudio de corte transversal con 204 trabajadores, 71 expuestos a disolventes orgánicos procedentes de la Fábrica de Calzado de Canastilla "Capitán San Luis" y 133 controles que laboran en la Empresa Complejo Lácteo de la Habana, con el fin
Heliodora Díaz Padrón, María Esther Linares Fernández, Manuel Perdomo Novas, Gladys Rabelo Padua, Pedro González Almeida   +4 more
doaj  

Chemical composition and insecticidal effects of Citrus aurantium essential oil and its powdery formulation against Tuta absoluta. Zarrad, K., Chaieb, I., Ben Hamouda, A., Bouslama, T., and Laarif, A. (Tunisia) [PDF]

Tunisian Journal of Plant Protection, 2017
The aim of this research was to investigate the chemical composition and to evaluate the insecticidal activities of the bitter orange Citrus aurantium essential oil and its major compound pure limonene against adults and larvae of the tomato miner Tuta ...
Khaoula Zarrad, Ikbal Chaieb, Amel Ben Hamouda, Thameur Bouslama, Asma Laarif   +4 more
doaj