Results 41 to 50 of about 5,665,112 (248)

Chemical Constituents from and

open access: yesNatural Product Communications, 2014
A new naphthoquinone, 6-methoxy-7-hydroxy-α-dunnione (1) , along with four known compounds ( 2, 4, 10 , and 11 ) were isolated from Snningia canescens (Mart.) Wiehler tubers, while S.
Maria Helena Verdan   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Chemical Constituents of Pteris longifolia

open access: yes, 1978
Department of Chemistry, University of Kalyani, Kalyani, Nadia, West Bengal Manuscript received 24 May 1977, accepted J October 1977 Chemical Constituents of Pteris ...
(MISS) USHA SARKAK, (Miss) MANJU SBN
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Chemical constituents of Saussurea laniceps

open access: yes, 2008
Aim: To study the chemical constituents of Saussurea laniceps. Methods: The chemical constituents were isolated and purified by various chromatographic techniques.
Li, GR   +4 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Chemical constituents of tobacco smoke induce the production of interleukin-8 in human bronchial epithelium, 16HBE cells

open access: yes, 2016
Introduction Interleukin-8 (IL-8) functions as a major chemoattractant and plays pivotal roles in the initiation and development of chronic obstructive pulmonary disease (COPD), and tobacco smoke is a most risk factor contributing to the development of ...
Guojun Zhou   +8 more
core   +1 more source

Chemical constituents of volatile and non-volatile extracts of Oncoba spinosa (Forssk) [PDF]

open access: yes, 2019
The essential oils from the leaf and stem bark of Oncoba spinosa were obtained through hydro-distillation while the non-volatile leaf extracts were obtained by solvent extraction. The essential oils and silylated extracts were analysed using GC-MS.
Oladele Oladimeji, Abdulkabir   +3 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Chemical Constituents from the Fungus

open access: yesNatural Product Communications, 2019
A new benzenoid, 4-methoxy-7-methylbenzo[ d ][1,3]dioxol-5-ol ( 1 ) and three known secondary metabolites 2,3-dimethoxy-5-methyl[1,4]benzoquinone ( 2 ), 2-methoxy-6-methyl-1,4-benzoquinone ( 3 ) and 5-methyl-benzo[1,3]dioxole-4,7-diol ( 4 ) were isolated
Ming-Der Wu   +6 more
doaj   +1 more source

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