Results 51 to 60 of about 5,665,112 (248)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Chemical constituents of AVG and CAE.

open access: yes, 2016
Chemical constituents of AVG and CAE.
Mariko Moriyama (420974)   +9 more
core   +1 more source

Chemical Constituents from Stems of

open access: yesNatural Product Communications, 2019
Phytochemical investigation on the stems of Pileostegia viburnoides Hook.f.et Thoms led to the isolation of twelve compounds, including two steroids ( 1 and 10 ), two fatty compounds ( 2 and 12 ), seven triterpenoids ( 3 – 9 ), and one coumarin glycoside
Xiao-Jun Li   +6 more
doaj   +1 more source

Chemical Constituents and Neuroprotective Activity of

open access: yesNatural Product Communications, 2023
Objective/Background The Hypericum hookerianum is widely distributed in Asian countries and prevalently used in traditional herbal medicines for its significant antioxidant, antipyretic, and anticancer properties.
Vu Duy Hong   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Fenologia e prospecção fitoquímica do jaborandi (Pilocarpus microphyllus Stapf ex Holmes)

open access: yesRevista Brasileira de Plantas Medicinais
RESUMO O estudo fenológico tem como finalidade determinar o ritmo sazonal dos eventos do ciclo de vida da planta, como floração e frutificação. Estes eventos são determinados por uma série de fatores, como: alternância de períodos chuvosos ou não ...
C.S.A. OLIVEIRA   +4 more
doaj   +1 more source

Chemical constituents of Simarouba versicolor

open access: yesAnais da Academia Brasileira de Ciências, 2002
From the roots, stems and fruits of Simarouba versicolor (Simaroubaceae) were isolated quassinoids (3, 5-7), triterpenoids (8-14), a mixture of steroids (15-17), the flavonoid kaempferol (18) and the squalene derivative 11,14-diacetoxy-7,10; 15,18 ...
ANGELA M.C. ARRIAGA   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Chemical Constituents of Liposoluble Extract of Spiraea Hypericifolia L.

open access: yes, 2020
The genus Spiraea L., spirea, represents deciduous shrubs of the family Rosaceae Juss., subfamily Spiraeoideae Focke. The genus is widespread in the temperate and the subtropical zone of the northern hemisphere having more than 100 species.
Dyusebaeva Moldyr   +4 more
core   +1 more source

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