Waste residues produced by agricultural and forestry industries can generate energy and are regarded as a promising source of sustainable fuels. Pyrolysis, where waste biomass is heated under low-oxygen conditions, has recently attracted attention as a ...
Xing Yang +13 more
doaj +1 more source
Approximation of ground water quality for microbial and chemical contamination. [PDF]
Alsalme A, Al-Zaqri N, Ullah R, Yaqub S.
europepmc +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Chemical Contamination Pathways and the Food Safety Implications along the Various Stages of Food Production: A Review. [PDF]
Lebelo K +3 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Microbiological and chemical contamination in different types of food of non-European origin
In the markets of the European Union (EU) the presence of food imported from non-European countries such as Asia, Africa and America is increasingly more widespread. Non-European countries, indeed, are much more competitive in terms of prices compared to
Francesco Casalinuovo +3 more
doaj +1 more source
Study of the Characteristics and Comprehensive Fuzzy Assessment of Indoor Air Chemical Contamination in Public Buildings. [PDF]
Liang X, Li Z, Zhang H, Hong X.
europepmc +1 more source
Relations of environmental contaminants, algal toxins, and diet with the reproductive success of American alligators on Florida Lakes [PDF]
(113 page ...
Arnold, Beverly S. +3 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source

