Results 71 to 80 of about 7,370,554 (257)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Notulae Botanicae Horti Agrobotanici Cluj-NapocaFungal pathogens represent a major constraint for agricultural productivity, and plant secondary metabolites play an important role in natural defence mechanisms.
Anayancy LAM-GUTIÉRREZ +9 more
doaj +1 more source
Impedance Study of Electrochemical Stability Limits for Electrolytes
International Journal of Electrochemical Science, 2012 Aiming to accurately determine electrochemical stability for electrolytes with electrode of a high surface area in electrochemical capacitors, an impedance method is proposed based on the facts that the phase angle of the impedance curve will decrease as
Dong Chen +5 more
doaj +1 more source
Distribution of 238U, 232Th, 40K, and 137Cs concentrations in soil samples nearby a nuclear laboratory, Capao Island, Brazil [PDF]
Nuclear Technology and Radiation Protection, 2015 Absolute soil concentrations of 238U, 232Th, 40K, and 137Cs samples were measured using high-resolution gamma spectrometry. The area of interest encompasses an embankment in a mangrove swamp in Guaratiba, Rio de Janeiro, called Capao Island ...
Oliveira Luciano S.R. +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
, 1983 Includes bibliographical referencesThis paper examines the attempt made between 1976 and 1983 to significantly raise expenditure on defence, and to direct a higher proportion of the total to the purchase of equipment.
Woolner, Derek
core
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Are Toxic Butterflies More Easily Detected by Human ‘Predators’?
Ecology and EvolutionButterfly colours often signal unprofitability due to toxicity to predators, with more conspicuous colour signals increasing predator avoidance learning.
Marilia Fernandes Erickson +2 more
doaj +1 more source