Results 51 to 60 of about 42,897 (262)

Investment in seed physical defence is associated with species' light requirement for regeneration and seed persistence: evidence from Macaranga species in Borneo. [PDF]

PLoS ONE, 2014
The seed stage is often critical in determining the regeneration success of plants. Seeds must survive an array of seed predators and pathogens and germinate under conditions favourable for seedling establishment.
Pimonrat Tiansawat, Adam S Davis, Mark A Berhow, Paul-Camilo Zalamea, James W Dalling   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Are Toxic Butterflies More Easily Detected by Human ‘Predators’?

Ecology and Evolution
Butterfly colours often signal unprofitability due to toxicity to predators, with more conspicuous colour signals increasing predator avoidance learning.
Marilia Fernandes Erickson, Donald James McLean, Marie E. Herberstein   +2 more
doaj   +1 more source

Survival of Lassa Virus in Blood and Tissue Culture Media and in a Small Particle Aerosol

Pathogens, 2020
Knowledge of the survival and stability of a pathogen is important for understanding its risk, reducing its transmission, and establishing control measures.
Sophie J Smither, Lin S Eastaugh, James S Findlay, Lyn M O’Brien, Mark S Lever   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Local Air Defence Units of South-Eastern Regions of the Far East during the War with Japan in August-September 1945

Научный диалог, 2019
The activity of units of local air defence (LAD) of the South-Eastern regions of the Far East during the war with Japan in August-September 1945 is analyzed.
A. V. Drobnitsa, S. A. Bogdanov
doaj   +1 more source

A resonant cavity system for exposing cell cultures to intense pulsed RF fields

Scientific Reports, 2022
The IEEE and ICNIRP had specified a maximum permissible exposure for instantaneous peak electric field of 100 kV/m. However, no rationale was given for this limit.
Masood Ur-Rehman, Yasir Alfadhl, Xiaodong Chen, Rachel Whiting, Alex Wright, Christopher D. Lindsay, John Tattersall, Iain Scott   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source