Results 31 to 40 of about 42,897 (262)

Toxicity of the purple mucus of the polychaete Halla parthenopeia (Oenonidae) revealed by a battery of ecotoxicological bioassays

Scientia Marina, 2014
Mucus secretions play a number of functions related to polychaete physiology and ecology. Under stress conditions, the polychaete Halla parthenopeia (Oenonidae) produces a purple mucus after mechanical stimulation, whose function is still unknown.
Dario Iori, Luca Forti, Gloria Massamba-N’Siala, Daniela Prevedelli, Roberto Simonini   +4 more
doaj   +1 more source

Diet and chemical defence in ladybird beetles (Coleoptera: Coccinellidae)

European Journal of Entomology, 2022
In this paper, I review the effects of the diet of ladybirds on chemical defence in this group of beetles. The tendency to reflex bleed and the diversity of autogenously produced alkaloids in different taxa may be evolutionarily related to diet and the ...
John J. SLOGGETT
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Survival and persistence of Nipah virus in blood and tissue culture media

Emerging Microbes and Infections, 2019
Nipah virus (NiV) infection is a newly emerging zoonosis that causes severe disease in humans. Nipah virus is one of the lesser studied of the WHO emerging pathogens for which research is a priority.
Sophie J. Smither, Lin S. Eastaugh, James S. Findlay, Lyn M. O’Brien, Ruth Thom, Mark S. Lever   +5 more
doaj   +1 more source

Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice

Toxics, 2022
The therapeutic efficacy of treatments for acute intoxication with highly toxic organophosphorus compounds, called nerve agents, usually involves determination of LD50 values 24 h after nerve agent challenge without and with a single administration of ...
Jiri Kassa, Christopher M. Timperley, Mike Bird, A. Christopher Green, John E. H. Tattersall   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Molecular basis of the explosive defence response in the bombardier beetle Brachinus crepitans

Royal Society Open Science
Bombardier beetles have evolved a sophisticated and unique chemical defence mechanism involving controlled explosions within their paired defensive glands, producing a hot, benzoquinone-rich defensive spray.
Heiko Vogel, Nicolai Rügen, Natalie Wielsch, Richard M. Twyman, Miray Tonk-Rügen, Andreas Vilcinskas   +5 more
doaj   +1 more source

An Enzyme-Based Biosensor for the Detection of Organophosphate Compounds Using Mutant Phosphotriesterase Immobilized onto Reduced Graphene Oxide

Journal of Chemistry, 2021
Enzymatic detection of organophosphate (OP) compounds can be tailored using highly sensitive and selective enzymes in the development of biosensors.
Muhammad Syafiq Mohd Razib, Wahhida Latip, Jahwarhar Izuan Abdul Rashid, Victor Feizal Knight, Wan Md Zin Wan Yunus, Keat Khim Ong, Noor Azilah Mohd Kasim, Siti Aminah Mohd Noor   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nano-Magnetic Immunosensor Based on Staphylococcus Protein A and the Amplification Effect of HRP-Conjugated Phage Antibody

Sensors, 2015
In this research, super-paramagnetic Fe3O4 nanoparticles (magnetic particles) were coated with Staphylococcus protein A (SPA) and coupled with polyclonal antibody (pcAb) to construct magnetic capturing probes, and HRP-conjugated phage antibody was then ...
Xihui Mu, Zhaoyang Tong, Qibin Huang, Bing Liu, Zhiwei Liu, Lanqun Hao, Jinping Zhang, Chuan Gao, Fenwei Wang   +8 more
doaj   +1 more source