Results 121 to 130 of about 4,478,531 (313)

Ancient Merv, Turkmenistan: research, conservation and management at a World Heritage Site [PDF]

, 2002
n the first issue of AI, Georgina Herrmann described the Institute’s initial involvement, from 1992, in survey, recording and excavation at the ancient Silk Road site of Merv.
Williams, T
core   +2 more sources

Chemical cues linked to risk: Cues from below‐ground natural enemies enhance plant defences and influence herbivore behaviour and performance

Functional Ecology, 2019
Chemical cues are essential for many ecological interactions. Previous studies of chemically mediated multitrophic interactions have typically focused on responses to cues from plants or herbivores above‐ground.
A. Helms, Swayamjit Ray, Nina L. Matulis, Margaret C. Kuzemchak, William Grisales, J. Tooker, J. Ali   +6 more
semanticscholar   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Associational resistance or susceptibility:the indirect interaction between chemically-defended and non-defended herbivore prey via a shared predator [PDF]

, 2016
Many organisms possess chemical defences against their natural enemies, which render them unpalatable or toxic when attacked or consumed. These chemically-defended organisms commonly occur in communities with non- or less-defended prey, leading to ...
Barbosa, Bates, Boivin, Bridges, Castagneyrol, Chaplin-Kramer, Charnov, Daly, Denno, Eigenbrode, Eigenbrode, Eisner, Fagerström, Fournier, Francis, Fry, Halkier, Hay, Heller, Holt, Holt, Holt, Holt, Hopkins, Kalule, Kalule, Kats, Kazana, Kos, Kos, Kostenko, Lindquist, MacArthur, McCall, Müller, Nesbit, Nesbit, Opitz, Pace, Prasad, Schmitz, Scrucca, Sherratt, Staley, Trumble, Underwood, van Dam, van Veen, van Veen, Vlieger, Wahl, Williams, Zuur   +52 more
core   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Security risk assessment and protection in the chemical and process industry [PDF]

, 2014
This article describes a security risk assessment and protection methodology that was developed for use in the chemical- and process industry in Belgium. The approach of the method follows a risk-based approach that follows desing principles for chemical
American Petroleum Institute, Arata, Cameron, Dowell, Ellis, Fennelly, Fontaine, Gabbar, Garcia, IAEA (International Atomic Energy Agency), Institute of Security Belgium, Kapp, Landoll, Mannan, Meyer, Norman, Reniers, Reniers, Reniers, Wu   +19 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Freedom From Torture in the "War on Terror": Is it Absolute? [PDF]

, 2011
Freedom from torture is regarded as “absolute,” meaning that a state cannot infringe the right for purposes which would seem legitimate such as the protection of national security.
Turner, Ian David
core   +1 more source

Bile acids in physico-chemical host defence

Pathophysiology, 2004
The discovery of the physico-chemical host defence is closely connected with the endotoxin research. It is well known that the toxic effects of endotoxins under experimental conditions can be induced only when they are administered parenterally. However, in naturally occurring entero-endotoxemic diseases (e.g.
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source