Results 101 to 110 of about 11,196 (277)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Chemical toxins and body defences.

Biologist (London, England), 2002
Without realising it, we are all exposed to a wide range of toxins every day. Some are a natural part of our diet and environment and some are man-made. Over evolutionary time, biochemical pathways are developed that have allowed our bodies to cope with this onslaught.
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Phylogenetic and biogeographical patterns in defensive strategies and quantitative allocation to chemical defences in Palaearctic and Nearctic pine trees

, 2014
Aim: Using pine trees as a long-lived woody plant model, we analysed the extent to which constitutive and induced allocation to chemical defences were conserved across the phylogeny, and tested the hypothesis that patterns of defensive allocation and
Vilà, Montserrat, Sampedro Pérez, Luis, Carrillo-Gavilán, Amparo, González-Voyer, Alejandro, Zas Arregui, Rafael, Moreira Tomé, Xoaquín   +5 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Dry up and survive: the role of antioxidant defences in anhydrobiotic organisms

Journal of Limnology, 2013
Although the evolution of life has turned oxygen into a vital chemical for aerobic organisms, this element can also have deleterious effects on living systems through the production of oxidative stress.
Lorena Rebecchi
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Threat to the predator suppresses defence of its prey

Royal Society Open Science
Many studies have shown that prey can optimize their defence mechanisms based on cues indicating predator presence and pressure. However, little is known about whether prey can assess the actual threat by considering both predator density and the ...
Monika Sysiak, Piotr Maszczyk, Andrzej Mikulski   +2 more
doaj   +1 more source

Pollen chemical and mechanical defences restrict host-plant use by bees

<p>Plants produce an array of chemical and mechanical defences that provide protection against many herbivores and pathogens. Putatively defensive compounds and structures can even occur in floral rewards: for example, the pollen of some plant taxa
Muralidhar, Madhupreeta, Rivest, Sébastien, Forrest, Jessica   +2 more
core   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source