Results 61 to 70 of about 5,780,781 (282)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Ecology and EvolutionParents can invest in offspring by transferring environmental factors, such as nutrients or diet‐derived defence chemicals, into eggs or embryos. However, in systems where females can reproduce facultatively without a male (facultative parthenogenesis ...
Ana Caroline Oliveira Vasconcelos +2 more
doaj +1 more source
Epichloë endophytes alter inducible indirect defences in host grasses. [PDF]
PLoS ONE, 2014 Epichloë endophytes are common symbionts living asymptomatically in pooid grasses and may provide chemical defences against herbivorous insects. While the mechanisms underlying these fungal defences have been well studied, it remains unknown whether ...
Tao Li +4 more
doaj +1 more source
Towards Comparative Evaluation of DDoS Defences
, 2022 DDoS defence evaluation provides a way to capture the usefulness of defensive solutions to one of the most notorious Internet attacks of our computing generation.
Otung, A, Martin, A
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Defenses of whirligig beetles against native and invasive frogs [PDF]
PeerJMany native insects have evolved defenses against native predators. However, their defenses may not protect them from non-native predators due to a limited shared history.
Shinji Sugiura, Masakazu Hayashi
doaj +2 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Scientific Reports, 2021 If optimal investment in anti-predator defences depends on predation risk, invading new regions (and thus, encountering different predators) may favour shifts in that investment.
Cameron M. Hudson +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Pollen-feeding delays reproductive senescence and maintains toxicity of Heliconius erato
Peer Community JournalDietary shifts may act to ease energetic constraints and allow organisms to optimise life-history traits. Heliconius butterflies differ from other nectar-feeders due to their unique ability to digest pollen, which provides a reliable source of amino ...
Pinheiro de Castro, Erika C. +6 more
doaj +1 more source