Results 131 to 140 of about 1,425,518 (291)

Equalities in Scotland’s Growth Economic Sectors: Final Report [PDF]

open access: yes, 2015
Aims The purpose of the study was to examine equality issues in Scotland’s growth sectors since baseline research carried out in 2009, focusing on trends in the following protected characteristics: gender; age; disabilities; ethnic minorities; gender ...
Kromydas, Theocharis   +4 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Application of the CDIO Approach in Developing Student’s Chemistry Experimentation Competencies: Theory and Practice

open access: yesEducational Process: International Journal
Background/purpose. The current trend of training Chemistry teachers focuses on innovating pedagogical methods and developing students’ holistic competencies, particularly their chemistry experimentation competencies (CEC).
Giac Cu Cao   +4 more
doaj   +1 more source

Tracking Chart 2005 Reebok, Mexico 36025017D [PDF]

open access: yes, 2005
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Teachers’ perspective on the use of artificial intelligence on remote experimentation

open access: yesFrontiers in Education
Remote Laboratories have become crucial educational resources due to their implementation in institutions that have adopted hybrid teaching models. Moreover, artificial intelligence (AI) has increasingly been used to develop educational support tools ...
Fiorella Lizano-Sánchez   +4 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

ALTERNATIVE VERSIONS OF PERIODIC SYSTEM OF CHEMICAL ELEMENTS IN THE EDUCATIONAL PROCESS

open access: yesВысшее образование в России, 2016
The article addresses the problems relating to the use of the alternative periodic tables of chemical elements in studying of various chemical disciplines. The versions concerned are the so-called «short-form" table proposed by Dmitri Mendeleev and «long-
Oleg V. Mikhailov
doaj  

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