Results 51 to 60 of about 1,425,518 (291)

COEL: A Web-based Chemistry Simulation Framework [PDF]

open access: yes, 2014
The chemical reaction network (CRN) is a widely used formalism to describe macroscopic behavior of chemical systems. Available tools for CRN modelling and simulation require local access, installation, and often involve local file storage, which is ...
Banda, Peter   +2 more
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Optimizing Human–AI Collaboration in Chemistry: A Case Study on Enhancing Generative AI Responses through Prompt Engineering

open access: yesChemistry
“Are we asking the right questions?” seems cliché, but for ChatGPT, it is a pivotal tool to ensure the accuracy of responses. While ChatGPT-3.5’s training on the vast database promises to revolutionize STEM education and research, this investigation ...
Dinesh V. Vidhani, Manoharan Mariappan
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Negative Energy: Why Interdisciplinary Physics Requires Multiple Ontologies

open access: yes, 2013
Much recent work in physics education research has focused on ontological metaphors for energy, particularly the substance ontology and its pedagogical affordances.
Dreyfus, Benjamin W.   +5 more
core   +1 more source

The Spitzer c2d Survey Of Nearby Dense Cores. XI. Infrared And Submillimeter Observations Of CB130 [PDF]

open access: yes, 2011
We present new observations of the CB130 region composed of three separate cores. Using the Spitzer Space Telescope, we detected a Class 0 and a Class II object in one of these, CB130-1.
Bourke, Tyler L.   +8 more
core   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

NMRium: Teaching nuclear magnetic resonance spectra interpretation in an online platform

open access: yesBeilstein Journal of Organic Chemistry
NMRium is the first web-based software that allows displaying, processing, interpretation, and teaching of 1D and 2D NMR data in a user-friendly interface. It can import the most common data formats (e.g., JCAMP-DX, Bruker, Varian, and Jeol).
Luc Patiny   +8 more
doaj   +1 more source

Craqueamento térmico de alcanos: uma aula prática de química orgânica para a graduação Thermal cracking of alkanes: an undergratuate organic chemistry experiment

open access: yesQuímica Nova, 2005
In this work we describe an experiment for the thermal cracking of octane and heptane and the qualitative analyses of the products using the Baeyer test for unsaturated compounds and gas chromatographic analyses.
Silvio Cunha   +5 more
doaj   +1 more source

A simple theoretical, quantitative approach to help understand the titration of weak acids and bases

open access: yesChemistry Teacher International, 2021
What happens at the very beginning of the titration of a weak acid or base is a question sometimes asked by undergraduate students when introduced to the concept of buffer solution.
Arocena Miguel
doaj   +1 more source

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