Results 71 to 80 of about 1,425,518 (291)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Química Nova, 2013 This paper describes a three-week mini-project for an Experimental Organic Chemistry course. The activities include N-C cross-coupling synthesis of N-(4-methoxyphenyl) benzamide in an adapted microwave oven by a copper catalyst (CuI).
Michelle Dalmás +6 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Applied SciencesThis study explores the integration of digital media tools—specifically TikTok, online press news analysis, and digital portfolios—into pre-service chemistry teacher education to enhance student engagement, foster conceptual understanding, and highlight ...
Juan Peña-Martínez +4 more
doaj +1 more source
A pesquisa em Ensino de Química como área estratégica para o desenvolvimento da Química
Química Nova, 2013 This paper presents an overview of the development of chemical education as a research area and some of its contributions to society. Although science education is a relatively recent area of research, it went through an expressive development in the ...
Wildson Luiz Pereira dos Santos +1 more
doaj +1 more source
The use of simulations and videos in order to improve the learning of REDOX reactions in Engineering Degrees [PDF]
, 2016 Many students from secondary schools to universities in many countries struggle to learn chemistry and many do not succeed. Many high school and university students experience difficulties with fundamental ideas in chemistry [1].
López Guerrero, Gema +1 more
core
Syntheses, Structures, and Photoluminescence of 1-D Lanthanide Coordination Polymers [PDF]
, 2009 Five new lanthanide 1-D coordination polymers are reported which are formed from flexible salen type Schiff-base ligands H(2)L and H(2)L' (H(2)L = N, N(1)-ethylene bis(salicylideneimine); H(2)L' = N,N(1)-bis(3-methoxysalicylidene) ethylene-1,2-diamine ...
Jones, Richard A. +3 more
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
The Lingering Killer: Agent Orange [PDF]
, 2014 This paper explores the utilization of the chemical herbicide, Agent Orange, as it was sprayed over Vietnam during the Vietnam War in 1961 to 1971. The United States government, military, and corporations acted irresponsibly by creating the chemical and ...
Ungerfeld, Sharon
core +1 more source