Results 111 to 120 of about 11,219,681 (307)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Chemical and Biomolecular Engineering Departmental Newsletter - Fall 2009

, 2009
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core  

Pulsed plasma enhanced chemical vapor deposition of fluorocarbon thin films for dielectric applications [PDF]

, 1999
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1999.Includes bibliographical references.by Catherine B.
Labelle, Catherine B., 1972-
core  

Multi-Objective Optimization in Chemical Engineering: Developments and Applications

, 2013
10.1002/9781118341704Multi-Objective Optimization in Chemical Engineering: Developments and Applications1 ...
Rangaiah, G.P., Bonilla-Petriciolet, A.
core   +1 more source

Contact angle analysis of biocolonized stone surfaces: Comparative study of benchtop and portable approaches to advance on-site applications

iScience
Summary: While traditionally confined to laboratory settings, recent developments have enabled Water Contact Angle (WCA) measurements to be conducted on-site, under field conditions. This study presents a comparative evaluation of a conventional benchtop
Letizia Berti, Davide Gulotta, Federica Villa, Lucia Toniolo, Gabriele Gianini, Francesca Cappitelli, Sara Goidanich   +6 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Chemical and Biomolecular Engineering Departmental Newsletter - Spring 2005

, 2005
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core  

Retracted: Oxygen Mass Transfer in an Aerated Stirred Tank with Double Impellers: A Generalized Correlation Including Spacing Impact

International Journal of Chemical Engineering, 2017
International Journal of Chemical Engineering
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Modeling of Hydrodynamics of Agglomeration of Low-Grade Phosphorites in the Presence of Phosphate-Siliceous Shales and Oil Sludge

ChemEngineering
The purpose of this study is to develop a multiphysical model of agglomeration of low-grade phosphorites with the addition of phosphate-siliceous shales and oil sludge.
Saltanat Tleuova, Zhunisbek Turishbekov, Ayaulym Tileuberdi, Dana Pazylova, Iskandarbek Iristaev, Mariyam Ulbekova, Nurila Sagindikova   +6 more
doaj   +1 more source