Results 111 to 120 of about 2,590,467 (296)

Development of Functional Nanomaterials for Applications in Chemical Engineering. [PDF]

Nanomaterials (Basel), 2023
Cao M.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Emerging chemical engineering of exosomes as "bioscaffolds" in diagnostics and therapeutics. [PDF]

Genes Dis, 2023
Wang J, Wang M, Jiang N, Ding S, Peng Q, Zheng L.   +5 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Development of a heat transfer and artificial neural networks teaching laboratory practical for biotechnology students [PDF]

, 2008
The paper describes a newly developed laboratory practical that teaches students how to develop an Artificial Neural Network model and its possible use in bio-processing. An emphasis is placed on giving students "hands on" experience with bio-processing
Brabazon, Dermot, Foley, Greg, Freeland, Brian, Naher, Sumsun   +3 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Pilot-Scale Laboratory Instruction for ChE: the specific case of the Pilot-unit leading group [PDF]

, 2010
This paper presents an original approach for Chemical Engineering laboratory teaching that is currently applied at INP-ENSIACET (France). This approach, referred to as "pilot-unit leading group" is based on a partial management of the laboratories by the
Billet, Anne-Marie, Camy, Séverine, Coufort, Carole   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Integrating the circular economy model into the management and treatment of Fischer–Tropsch effluents—a conversion of waste to energy (biogas) opportunity

IET Renewable Power Generation
The Fischer–Tropsch (FT) process converts coal, biomass, or natural gas into liquid hydrocarbons via syngas generation and catalytic conversion. However, FT produces byproducts and effluents with substantial environmental consequences.
Mabatho Moreroa, Thapelo P. Malematja, Grace Nkechinyere Ijoma   +2 more
doaj   +1 more source

Bioactive cytochalasans from the desert soil-derived fungus Chaetomium madrasense 375 obtained via a chemical engineering strategy. [PDF]

Front Microbiol, 2023
Guo Q, Shen S, Wang X, Shi L, Ren Y, Li D, Yin Z, Zhang J, Yang B, Wang X, Ding G, Chen L.   +11 more
europepmc   +1 more source