Results 121 to 130 of about 11,219,681 (307)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Chemical and Biomolecular Engineering Departmental Newsletter - Fall 2005

open access: yes, 2005
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core  

Experimental and theoretical insight of nonisothermal adsorption kinetics for a single component adsorbent-adsorbate system

open access: yes, 2012
10.1021/je201210tJournal of Chemical and Engineering Data5741174 ...
Loh, W.S.   +7 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Chemical and Biomolecular Engineering Departmental Newsletter - Fall 2006

open access: yes, 2001
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core  

Bioactive cytochalasans from the desert soil-derived fungus Chaetomium madrasense 375 obtained via a chemical engineering strategy. [PDF]

open access: yesFront Microbiol, 2023
Guo Q   +11 more
europepmc   +1 more source

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