Results 141 to 150 of about 11,219,681 (307)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Chemical and Biomolecular Engineering Departmental Newsletter - Spring 2019

, 2019
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core  

Identical‐Location SEM Tracking of Pt/C Gas Diffusion Electrode Degradation at Fuel‐Cell‐Relevant Current Densities

ChemElectroChem
Understanding Pt/C catalyst degradation under relevant proton‐exchange membrane fuel cell (PEMFC) conditions remains challenging because most identical‐location studies are conducted under nonrepresentative conditions (rotating disk electrode ...
Aleš Marsel, Miha Hotko, Gregor Kapun, Marjan Bele, Lazar Bijelić, Enrico Petrucco, Christopher M. Zalitis, Alex Martinez Bonastre, Nejc Hodnik   +8 more
doaj   +1 more source

Pre-lab video demonstrations to enhance students' laboratory experience in a first-year chemical engineering class. [PDF]

Biochem Mol Biol Educ, 2023
Onyeaka H, Passaretti P, Miri T, Hart A, Favero C, Anumudu CK, Robbins P.   +6 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Chemical and Biomolecular Engineering Departmental Newsletter - Fall 2006

, 2006
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core  

Effects of PVdF Binder Molecular Weight and Active Material Morphology on Processing, Structure, and Performance of LiNi0.6Mn0.2Co0.2O2‐Based Positive Electrodes

Advanced Energy & Sustainability Research
Polyvinylidene difluoride (PVdF) is the most common binding agent for positive electrodes in lithium ion batteries. However, its processing solvent N‐methyl‐2‐pyrrolidone (NMP) poses safety and environmental risks and regulations increasingly demand its ...
Johanna Kauling, Candeniz Gercek, Jonas Fechner, Martin Winter, Markus Börner   +4 more
doaj   +1 more source

Catalytic confinement effects in nanochannels: from biological synthesis to chemical engineering. [PDF]

Nanoscale Adv, 2022
Shen Y, Wang X, Lei J, Wang S, Hou Y, Hou X.   +5 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Chemical and Biomolecular Engineering Departmental Newsletter - Spring 2006

, 2006
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core