Results 171 to 180 of about 10,459,426 (304)

Chemical and Biomolecular Engineering Departmental Newsletter - Spring 2012

open access: yes, 2012
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Chemical and Biomolecular Engineering Departmental Newsletter - Fall 2016

open access: yes, 2016
This quarterly newsletter provides information on students, faculty, alumni, and events from the Chemical and Biomolecular Engineering Department at Clemson ...
Clemson University. Chemical and Biomolecular Engineering Department
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

BatGPT-Chem: A Foundation Large Model for Chemical Engineering. [PDF]

open access: yesResearch (Wash D C)
Yang Y   +7 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A versatile platform for chemical engineering of exosomes empowered by ADP-ribosyl cyclases. [PDF]

open access: yesNat Commun
Zhang L   +11 more
europepmc   +1 more source

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