Results 31 to 40 of about 2,548,889 (328)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Chemically Engineering Magnetic Anisotropy of 2D Metalloporphyrin

Advanced Science, 2017
Continuous miniaturization of magnetic units in spintronics devices inspires efforts to search for novel 2D magnetic materials with giant magnetic anisotropy energy (MAE).
Peng Wang, Xue Jiang, Jun Hu, Jijun Zhao
doaj   +1 more source

The role of Computer Aided Process Engineering in physiology and clinical medicine [PDF]

, 2009
This paper discusses the potential role for Computer Aided Process Engineering (CAPE) in developing engineering analysis and design approaches to biological systems across multiple levels—cell signalling networks, gene, protein and metabolic networks ...
Allen, R., Bogle, I.D.L., Sumner, T.
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Case Based Reasoning for Chemical Engineering Design [PDF]

, 2008
With current industrial environment (competition, lower profit margin, reduced time to market, decreased product life cycle, environmental constraints, sustainable development, reactivity, innovation…), we must decrease the time for design of new ...
Aamodt, Avramenko, King, Kister, Kraslawski, Le Lann Jean Marc, Lopez-Arevalo, Mori, Negny Stéphane, Pajula, Schank, Smyth, Surma, Zadeh   +13 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

TERM FORMATION IN THE LEXICAL-SEMANTIC FIELD “CHEMICAL ENGINEERING” IN MODERN ENGLISH: STRUCTURAL AND DERIVATIONAL ASPECTS

Sovremennye Issledovaniâ Socialʹnyh Problem
Background. In modern linguistics, research is being carried out on the methods of term formation in the lexical-semantic fields of various spheres of human activity.
Nataliya N. Zyablova
doaj   +1 more source

CHEMEPASS – Innovative Tools to promote Chemical Engineering Mobility [PDF]

, 2009
CHEMEPASS – Innovative Tools to promote Chemical Engineering ...
Billet, Anne-Marie, Camy, Séverine, Coufort, Carole, Gagneur, Sébastien, Le Lann, Jean-Marc, Meyer, Michel   +5 more
core  

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Graphic constructions of characteristic diagrams in chemical engineering and the application of differential geometry [PDF]

Hemijska Industrija, 2012
Starting from the experimental concentration-time ( cA,t diagram this work gives the construction of the rate of reaction-time (rA,t diagram using the pure graphic method.
Pejović Branko B., Mićić Vladan M., Tomić Milorad V., Tadić Goran S., Jotanović Milovan B.   +4 more
doaj   +1 more source